Ppp3cb Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp3cb
protein phosphatase 3, catalytic subunit, beta isoform
MGI:107163

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp3cb^tm1Jmk/Ppp3cb^tm1Jmk Tg(Myh6-Mapk14)1Jmol/0 involves: 129S6/SvEvTac C57BL/6 * FVB	normal cardiovascular system phenotype	J:83547
Ppp3cb^tm1Jmk/Ppp3cb^tm1Jmk Tg(Myh6/tetO-Tnnc1I61Q)1Jmol/0 Tg(Myh6-tTA)55Rbns/0 involves: 129S6/SvEvTac FVB	decreased cardiac muscle contractility	J:234490
	increased heart left ventricle size	J:234490
	increased heart weight	J:234490
	thin interventricular septum	J:234490
Rcan1^tm1Jmol/Rcan1^tm1Jmol Rcan2^tm1Jmol/Rcan2^tm1Jmol Ppp3cb^tm1Jmk/Ppp3cb^tm1Jmk involves: 129S6/SvEvTac * C57BL/6	abnormal CD4-positive, alpha beta T cell morphology	J:109586
	abnormal CD4-positive, alpha-beta T cell physiology	J:109586
	abnormal CD8-positive, alpha beta T cell morphology	J:109586
	abnormal cytokine secretion	J:109586
	decreased response of heart to induced stress	J:109586
	decreased T cell proliferation	J:109586
	hyperactivity	J:109586

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24