Ccr5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccr5
C-C motif chemokine receptor 5
MGI:107182

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Ccr5^tm1Blck/Ccr5^tm1Blck involves: 129P2/OlaHsd * C57BL/6	abnormal cytokine secretion	J:128063
	abnormal lymphocyte physiology	J:128063
	abnormal mononuclear phagocyte morphology	J:128063
	atherosclerotic lesions	J:128063
	decreased interferon-gamma secretion	J:128063
	decreased T cell number	J:128063
	increased interleukin-10 secretion	J:128063
Apoe^tm1Unc/Apoe^tm1Unc Ccr5^tm1Kuz/Ccr5^tm1Kuz involves: 129P2/OlaHsd * C57BL/6	abnormal cytokine secretion	J:128063
	abnormal lymphocyte physiology	J:128063
	abnormal mononuclear phagocyte morphology	J:128063
	abnormal vascular smooth muscle morphology	J:128063
	atherosclerotic lesions	J:128063
	decreased interferon-gamma secretion	J:128063
	decreased T cell number	J:128063
	increased interleukin-10 secretion	J:128063
Ccr5^tm1(CCR5)Pfi/Ccr5^tm1(CCR5)Pfi involves: C57BL/6	normal cardiovascular system phenotype	J:227458
Ccr5^tm1(CCR5)Pfi/Ccr5^tm1(CCR5)Pfi involves: C57BL/6	increased physiological sensitivity to xenobiotic	J:227458
Ccr5^tm1Kuz/Ccr5^tm1Kuz Cxcr4^tm1Qma/Cxcr4^tm1Qma involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	abnormal nervous system physiology	J:132342
	decreased susceptibility to Retroviridae infection	J:132342

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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