Coq7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Coq7
demethyl-Q 7
MGI:107207

19 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Coq7^{em1(IMPC)Hmgu}/Coq7^{em1(IMPC)Hmgu} C57BL/6N-Coq7^{em1(IMPC)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773
Coq7^tm1Hek/Coq7⁺ B6.129-Coq7^tm1Hek	extended life span	J:102109
Coq7^tm1Hek/Coq7⁺ involves: 129S1/Sv * 129X1/SvJ	extended life span	J:102109
Coq7^tm1Hek/Coq7⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal mitochondrial physiology	J:278535
Coq7^tm1Hek/Coq7⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c	extended life span	J:102109
Coq7^tm1Hek/Coq7^tm1Hek involves: 129S1/Sv * 129X1/SvJ	decreased embryo size	J:73121
	embryonic growth retardation	J:73121
	embryonic lethality during organogenesis, complete penetrance	J:73121
Coq7^tm1Hek/Coq7^tm2Hek Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S6/SvEvTac * C57BL/6NTac	abnormal liver physiology	J:202240
	abnormal respiratory electron transport chain	J:202240
	normal liver/biliary system phenotype	J:202240
	normal mortality/aging	J:202240
Coq7^tm1Tsh/Coq7^tm1Tsh involves: C57BL/6	abnormal aerobic respiration	J:73111
	abnormal embryonic neuroepithelial layer differentiation	J:73111
	abnormal lysosome morphology	J:73111
	abnormal mitochondrial morphology	J:73111
	decreased cell proliferation	J:73111
	decreased embryo size	J:73111
	embryonic lethality during organogenesis, complete penetrance	J:73111
	open neural tube	J:73111
Coq7^tm2.1Hek/Coq7^tm2.1Hek involves: 129S6/SvEvTac * C57BL/6NTac * FVB/N	preweaning lethality, complete penetrance	J:202240
Coq7^tm2Hek/Coq7^tm2Hek involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:202240
Coq7^tm2Hek/Coq7^tm2Hek involves: 129S6/SvEvTac * C57BL/6NTac	abnormal respiratory electron transport chain	J:202240
	normal cellular phenotype	J:202240
	increased cell death	J:202240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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