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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tinf2
Terf1 (TRF1)-interacting nuclear factor 2
MGI:107246
17 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tinf2tm1Yjc/Tinf2tm1Yjc
involves: 129S1/Sv * C57BL/6
embryonic lethality between implantation and somite formation, complete penetrance J:92239
Tinf2tm2.1Tdl/Tinf2+
Tg(CMV-cre)1Cgn/0
involves: BALB/cJ * C57BL/6
decreased birth body size J:207367
decreased body weight J:207367
prenatal lethality, incomplete penetrance J:207367
Tinf2tm2.1Tdl/Tinf2tm2.1Tdl
involves: C57BL/6
no abnormal phenotype detected J:207367
Tinf2tm2.2Tdl/Tinf2+
involves: BALB/cJ * C57BL/6
decreased telomere length J:207367
dermatitis J:207367
gliosis J:207367
hydrocephaly J:207367
lymphoid hyperplasia J:207367
myeloid hyperplasia J:207367
pancytopenia J:207367
reduced fertility J:207367
seizures J:207367
seminiferous tubule degeneration J:207367
testicular atrophy J:207367
Tinf2tm2.2Tdl/Tinf2tm2.2Tdl
involves: BALB/cJ * C57BL/6
embryonic lethality, complete penetrance J:207367

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory