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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bmp8b
bone morphogenetic protein 8b
MGI:107335
25 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmp8btm1Blh/Bmp8b+
either: B6.129-Bmp8btm1Blh or (involves: 129 * Black Swiss * C57BL/6) 		decreased primordial germ cell number J:63160
Bmp8btm1Blh/Bmp8btm1Blh
B6.129-Bmp8btm1Blh 		absent allantois J:63160
absent primordial germ cells J:63160
delayed embryo turning J:63160
embryonic growth retardation J:63160
embryonic lethality during organogenesis, incomplete penetrance J:63160
small allantois J:63160
Bmp8btm1Blh/Bmp8btm1Blh
either: B6.129-Bmp8btm1Blh or (involves: 129 * Black Swiss * C57BL/6) 		absent allantois J:63160
absent primordial germ cells J:63160
delayed embryo turning J:63160
small allantois J:63160
Bmp8btm1Blh/Bmp8btm1Blh
involves: 129/Sv * Black Swiss 		abnormal allantois morphology J:63160
abnormal cell differentiation J:34057
abnormal male germ cell morphology J:34057
abnormal primordial germ cell morphology J:63160
abnormal reproductive system physiology J:63160
abnormal seminiferous tubule epithelium morphology J:34057, J:46927
abnormal spermatogenesis J:34057
abnormal spermatogonia proliferation J:34057
absent primordial germ cells J:63160
decreased male germ cell number J:34057
decreased primordial germ cell number J:63160
decreased testis weight J:34057
delayed allantois development J:63160
embryonic growth retardation J:63160
increased Leydig cell number J:34057
increased male germ cell apoptosis J:34057
male infertility J:34057
seminiferous tubule degeneration J:34057, J:46927
small allantois J:63160
small seminiferous tubules J:34057
small testis J:34057, J:46927
testis degeneration J:34057
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory