Ctss Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctss
cathepsin S
MGI:107341

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctss^tm1Hap/Ctss^tm1Hap Dmd^mdx/Dmd^mdx involves: 129S2/SvPas * C57BL/10ScSn	abnormal skeletal muscle fiber morphology	J:230788
	centrally nucleated skeletal muscle fibers	J:230788
	dystrophic muscle	J:230788
	impaired exercise endurance	J:230788
	increased circulating creatine kinase level	J:230788
	skeletal muscle fiber necrosis	J:230788
	skeletal muscle fibrosis	J:230788
Ctss^tm1Hap/Ctss^tm1Hap Ldlr^tm1Her/Ldlr^tm1Her B6.129S-Ctss^tm1Hap Ldlr^tm1Her	abnormal leukocyte migration	J:82520
	decreased circulating cholesterol level	J:82520
	decreased circulating LDL cholesterol level	J:82520
	decreased susceptibility to atherosclerosis	J:82520
	vascular smooth muscle hypoplasia	J:82520
Ctss^tm1Hap/Ctss^tm1Hap Tg(Scgb1a1-rtTA,tetO-Ifng)14Eli/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal lung volume	J:100854
	emphysema	J:100854
	increased apoptosis	J:100854
	increased lung compliance	J:100854
	increased lymphocyte cell number	J:100854
	increased macrophage cell number	J:100854
	increased neutrophil cell number	J:100854

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24