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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Inpp5d
inositol polyphosphate-5-phosphatase D
MGI:107357
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Inpp5dtm1Rav/Inpp5dtm1Rav
Ptentm1Hwu/Ptentm1Hwu
involves: 129P2/OlaHsd * 129S4/SvJae 		abnormal B cell morphology J:166155
abnormal B cell physiology J:166155
abnormal coat appearance J:166155
abnormal myeloid leukocyte morphology J:166155
decreased B cell number J:166155
enlarged spleen J:166155
hunched posture J:166155
increased B cell number J:166155
increased B cell proliferation J:166155
increased follicular lymphoma incidence J:166155
increased lymphoma incidence J:166155
increased malignant tumor incidence J:166155
increased plasmacytoma incidence J:166155
increased spleen white pulp amount J:166155
increased splenic marginal zone lymphoma incidence J:166155
lethargy J:166155
premature death J:166155
weight loss J:166155
Il6tm1Kopf/Il6tm1Kopf
Inpp5dtm1Rkh/Inpp5dtm1Rkh
involves: 129 * C57BL/6 		abnormal hematopoietic stem cell morphology J:117320
abnormal lymphopoiesis J:117320
abnormal myelopoiesis J:117320
decreased pro-B cell number J:117320
Inpp5dtm1Rav/Inpp5dtm1Rav
Cd79atm1(cre)Reth/Cd79a+
Tg(IghAb36-65)1Wys/0
involves: 129 * BALB/c * C57BL/6 * FVB/N 		abnormal B cell anergy J:178833
abnormal B cell negative selection J:178833
decreased B cell number J:178833
increased autoantibody level J:178833
increased plasma cell number J:178833
Inpp5dtm1Rkh/Inpp5dtm1Rkh
Rag1tm1(GFP)Imku/Rag1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal lymphopoiesis J:117320
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory