Stxbp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stxbp1
syntaxin binding protein 1
MGI:107363

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stxbp1^{tm1b(EUCOMM)Hmgu}/Stxbp1⁺ C57BL/6N-Stxbp1^{tm1b(EUCOMM)Hmgu}/J	abnormal auditory brainstem response	J:211773
	decreased hematocrit	J:211773
	hyperactivity	J:211773
	impaired glucose tolerance	J:211773
	increased exploration in new environment	J:211773
	increased grip strength	J:211773
	increased mean corpuscular volume	J:211773
	increased thigmotaxis	J:211773
Stxbp1^{tm1b(EUCOMM)Hmgu}/Stxbp1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Stxbp1^{tm1b(EUCOMM)Hmgu}/J	abnormal embryo size	J:211773
	edema	J:211773
	hemorrhage	J:211773
	preweaning lethality, complete penetrance	J:211773
Stxbp1^tm1Mver/Stxbp1^tm1Mver Tg(Pcp2-cre)2Mpin/0 involves: 129S1/Sv * 129X1/SvJ	ataxia	J:100337
	decreased Purkinje cell number	J:100337
Stxbp1^tm1Sud/Stxbp1^tm1Sud Not Specified	abnormal neurotransmitter secretion	J:77237, J:100337
	abnormal synaptic transmission	J:77237
	axon degeneration	J:85723
	neonatal lethality, complete penetrance	J:77237
	normal nervous system phenotype	J:77237
	neurodegeneration	J:77237
	neuron degeneration	J:100337

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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