Il17a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il17a
interleukin 17A
MGI:107364

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adam17^tm1.2Bbl/Adam17^tm1.2Bbl Il17a^tm1Yiw/Il17a^tm1Yiw Sox9^tm3(cre)Crm/Sox9⁺ involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL	dermatitis	J:229771
Card14^em2Tshu/Card14⁺ Il17a^tm1Cdon/Il17a^tm1Cdon involves: C57BL/6	prenatal lethality, complete penetrance	J:289239
Card14^em3Tshu/Card14⁺ Il17a^tm1Cdon/Il17a^tm1Cdon involves: C57BL/6	decreased inflammatory response	J:289239
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Il17a^tm1Yiw/Il17a⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased survivor rate	J:191090
	glomerulonephritis	J:191090
	increased plasma cell number	J:191090
	increased spleen germinal center number	J:191090
	kidney inflammation	J:191090
	premature death	J:191090
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Il17a^tm1Yiw/Il17a^tm1Yiw involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased survivor rate	J:191090
	decreased susceptibility to systemic lupus erythematosus	J:191090
	increased anti-double stranded DNA antibody level	J:191090
	increased anti-nuclear antigen antibody level	J:191090
	increased double-negative T cell number	J:191090
	increased plasma cell number	J:191090
	increased spleen germinal center number	J:191090
	premature death	J:191090
Il1rn^tm1Yiw/Il1rn^tm1Yiw Il17a^tm1Yiw/Il17a⁺ involves: 129P2/OlaHsd * BALB/cA * C57BL/6J	decreased susceptibility to induced arthritis	J:83408
Il17a^tm1Yiw/Il17a^tm1Yiw Il1rn^tm1Yiw/Il1rn^tm1Yiw involves: 129P2/OlaHsd * BALB/cA * C57BL/6J	decreased susceptibility to induced arthritis	J:83408
Il17a^tm1Yiw/Il17a^tm1Yiw Il17f^tm1Yiw/Il17f^tm1Yiw involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to bacterial infection	J:143719
Il17a^tm1Yiw/Il17a^tm1Yiw Il17f^tm1Yiw/Il17f^tm1Yiw Il1rn^tm1Yiw/Il1rn^tm1Yiw involves: 129 * BALB/c	rheumatoid arthritis	J:143719
Il17a^tm1Yiw/Il17a^tm1Yiw Il17f^tm2Yiw/Il17f^tm2Yiw B6.129P2-Il17a^tm1Yiw Il17f^tm2Yiw	decreased IgG3 level	J:143719
	enlarged submandibular lymph nodes	J:143719
	increased IgG1 level	J:143719
	increased IgG2a level	J:143719
	increased IgG2b level	J:143719
	increased susceptibility to infection induced morbidity/mortality	J:160680
Il17a^tm1Yiw/Il17a^tm1Yiw Il17f^tm2Yiw/Il17f^tm2Yiw involves: 129P2/OlaHsd * BALB/c	decreased IgG3 level	J:143719
	enlarged submandibular lymph nodes	J:143719
	increased IgG1 level	J:143719
	increased IgG2a level	J:143719
	increased IgG2b level	J:143719
	increased susceptibility to bacterial infection	J:143719
	mouth mucosal ulcer	J:143719
	nasal inflammation	J:143719
Il17a^tm1Yiw/Il17a^tm1Yiw Il22^tm1Flv/Il22^tm1Flv involves: 129/Sv * 129P2/OlaHsd * C57BL/6	increased physiological sensitivity to xenobiotic	J:126103
Il17a^tm1Yiw/Il17a^tm1Yiw Tg(CD2-Rorc)#Staka/0 involves: 129P2/OlaHsd * C57BL/6	decreased salivation	J:230700
	increased susceptibility to autoimmune disorder	J:230700

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24