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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pitx1
paired-like homeodomain transcription factor 1
MGI:107374
54 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pitx1em1(IMPC)Wtsi/Pitx1+
C57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg 		abnormal autopod morphology J:211773
abnormal cornea morphology J:211773
abnormal digit morphology J:211773
abnormal femur morphology J:211773
abnormal joint morphology J:211773
abnormal nail morphology J:211773
abnormal tibia morphology J:211773
fused phalanges J:211773
polysyndactyly J:211773
vertebral transformation J:211773
Pitx1em1(IMPC)Wtsi/Pitx1em1(IMPC)Wtsi
C57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg 		preweaning lethality, complete penetrance J:211773
Pitx1tm1Jdr/Pitx1tm1Jdr
involves: 129S1/Sv * 129X1/SvJ 		abnormal cartilage morphology J:80020
abnormal fibula morphology J:80020
abnormal hindlimb morphology J:80020
abnormal pelvic girdle bone morphology J:80020
abnormal tibia morphology J:80020
absent ilium J:80020
hindlimb oligodactyly J:80020
short femur J:80020
small limb buds J:80020
Pitx1tm1Jdr/Pitx1tm1Jdr
involves: 129S1/Sv * 129X1/SvJ * BALB/c 		abnormal cartilage morphology J:52671
abnormal hindlimb morphology J:52671
abnormal long bone epiphyseal plate morphology J:52671
abnormal Meckel's cartilage morphology J:52671
abnormal middle ear ossicle morphology J:52671
abnormal pelvic girdle bone morphology J:52671
abnormal tibia morphology J:52671
absent gonial bone J:52671
absent ilium J:52671
absent patella J:52671
absent sesamoid bone of gastrocnemius J:52671
bifurcated tongue J:52671
cleft secondary palate J:52671
decreased tympanic ring size J:52671
failure of palatal shelf elevation J:52671
increased width of hypertrophic chondrocyte zone J:52671
micrognathia J:52671
perinatal lethality, complete penetrance J:52671
short femur J:52671
short hindlimb J:52671
short tibia J:52671
small ischium J:52671
small pubis J:52671
Pitx1tm1Rsd/Pitx1+
involves: 129S1/Sv * 129X1/SvJ 		abnormal adipose tissue amount J:175799
abnormal artery morphology J:175799
abnormal postnatal growth J:175799
clubfoot J:175799
decreased bone volume J:175799
muscle hypoplasia J:175799
Pitx1tm1Rsd/Pitx1tm1Rsd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal femur morphology J:53310
abnormal fibula morphology J:53310
abnormal hindlimb morphology J:53310
abnormal pelvic girdle bone morphology J:53310
abnormal pituitary gland morphology J:53310
abnormal tarsal bone morphology J:53310
abnormal tibia morphology J:53310
absent patella J:53310
absent submandibular gland J:53310
brachydactyly J:53310
cleft palate J:53310
decreased gonadotroph cell number J:53310
decreased thyrotroph cell number J:53310
embryonic lethality during organogenesis, incomplete penetrance J:53310
neonatal lethality, complete penetrance J:53310
short hindlimb J:53310
short mandible J:53310
short tongue J:53310
small mandible J:53310
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory