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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zbtb17
zinc finger and BTB domain containing 17
MGI:107410
36 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zbtb17tm1Cksn/Zbtb17tm1.1Cksn
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		rough coat J:123966
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Commd10Tg(Vav1-icre)A2Kio/Commd10+
B6.Cg-Zbtb17tm1Cksn Commd10Tg(Vav1-icre)A2Kio 		arrested T cell differentiation J:170508
decreased DN1 thymic pro-T cell number J:170508
decreased DN2 thymocyte number J:170508
decreased DN3 thymocyte number J:170508
decreased double-negative T cell number J:170508
decreased gamma-delta T cell number J:170508
decreased T cell number J:170508
decreased thymocyte number J:170508
increased T cell apoptosis J:170508
thymus hypoplasia J:170508
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal coat/ hair morphology J:123966
abnormal epidermal layer morphology J:123966
abnormal hair follicle melanocyte morphology J:123966
abnormal hair follicle morphology J:123966
abnormal hair follicle orientation J:123966
darkened coat color J:123966
decreased curvature of zigzag hairs J:123966
decreased zigzag hair amount J:123966
focal dorsal hair loss J:123966
hyperkeratosis J:123966
increased keratinocyte proliferation J:123966
rough coat J:123966
sparse hair J:123966
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Tg(Lck-cre)548Jxm/0
B6.Cg-Zbtb17tm1Cksn Tg(Lck-cre)548Jxm 		normal immune system phenotype J:170508
Zbtb17tm1Elr/Zbtb17tm1Elr
involves: 129X1/SvJ * C57BL/6 		abnormal developmental patterning J:86265
abnormal ectoderm development J:86265
abnormal embryonic tissue morphology J:86265
abnormal extraembryonic tissue morphology J:86265
abnormal primitive streak morphology J:86265
absent proamniotic cavity J:86265
decreased cell proliferation J:86265
decreased embryo size J:86265
embryonic growth retardation J:86265
embryonic lethality between somite formation and embryo turning, complete penetrance J:86265
failure to gastrulate J:86265
increased apoptosis J:86265
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory