Irak1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irak1
interleukin-1 receptor-associated kinase 1
MGI:107420

6 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irak1^tm1.1Pcoh/? involves: 129P2/OlaHsd	decreased interferon-alpha secretion	J:205798
Irak1^tm1.1Pcoh/? involves: 129P2/OlaHsd	normal immune system phenotype	J:205798
Irak1^tm1.1Pcoh/Y involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:179219
Irak1^tm1.1Pcoh/Irak1^tm1.1Pcoh involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:179219
Irak1^{tm1b(EUCOMM)Hmgu}/Y C57BL/6N-Irak1^{tm1b(EUCOMM)Hmgu}/Wtsi	increased circulating fructosamine level	J:211773
Irak1^tm1Jth/Y B6.Cg-Irak1^tm1Jth	decreased susceptibility to experimental autoimmune encephalomyelitis	J:82302
Irak1^tm1Jth/Irak1^tm1Jth B6.Cg-Irak1^tm1Jth	decreased susceptibility to experimental autoimmune encephalomyelitis	J:82302
Irak1^tm1Wpfl/Irak1^tm1Wpfl involves: 129P2/OlaHsd * C57BL/6J	abnormal cell physiology	J:110860

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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