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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Irak1
interleukin-1 receptor-associated kinase 1
MGI:107420
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Irak1tm1.1Pcoh/?
Irak2tm1.1Pcoh/?
involves: 129P2/OlaHsd * C57BL/6
decreased interferon-alpha secretion J:205798
Irak1tm1Jth/Irak1tm1Jth
Tg(Myh6-Tnf)1Brgi/?
involves: 129/Sv * C57BL/6J * SJL
abnormal heart morphology J:84829
normal mortality/aging J:84829
myocardial fiber degeneration J:84829
myocarditis J:84829
Irak1tm1Jth/Y
Irak2tm1Aki/Irak2tm1Aki
involves: 129/Sv * C57BL/6
abnormal dendritic cell physiology J:136290
abnormal macrophage physiology J:136290
decreased susceptibility to endotoxin shock J:136290
Irak1tm1Jth/Y
Tg(Myh6-Tnf)1Brgi/?
involves: 129/Sv * C57BL/6J * SJL
abnormal heart morphology J:84829
normal mortality/aging J:84829
myocardial fiber degeneration J:84829
myocarditis J:84829

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory