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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Capn3
calpain 3
MGI:107437
20 phenotypes from 12 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Capn3Gt(OST141731)Lex/Capn3Gt(OST141731)Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal A band morphology J:91206
abnormal diaphragm morphology J:91206
abnormal gastrocnemius morphology J:91206
abnormal muscle morphology J:91206
abnormal skeletal muscle fiber morphology J:91206
abnormal soleus morphology J:91206
abnormal tibialis anterior morphology J:91206
decreased body weight J:91206
decreased skeletal muscle mass J:91206
Capn3tm1.1Hiso/Capn3tm1.1Hiso
B6.129P2-Capn3tm1.1Hiso 		abnormal skeletal muscle fiber morphology J:163711
centrally nucleated skeletal muscle fibers J:163711
decreased skeletal muscle fiber diameter J:163711
dystrophic muscle J:163711
increased circulating creatine kinase level J:163711
skeletal muscle degeneration J:163711
Capn3tm1Jsb/Capn3tm1Jsb
either: 129/Sv-Capn3tm1Jsb or (involves: 129/Sv * C57BL/6) 		abnormal sarcolemma morphology J:66862
dystrophic muscle J:66862
transmission ratio distortion J:66862
Tg(ACTA1-Capn3)7.2Spc/0
involves: BALB/c * C57BL/6J 		centrally nucleated skeletal muscle fibers J:77348
normal muscle phenotype J:77348
Tg(ACTA1-Capn3*)10.2Spc/0
involves: BALB/c * C57BL/6J 		no abnormal phenotype detected J:77348
Tg(ACTA1-Capn3*)10.3Spc/0
involves: BALB/c * C57BL/6J 		centrally nucleated skeletal muscle fibers J:77348
Tg(ACTA1-Capn3*)27.10Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Tg(ACTA1-Capn3*)37.3Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Tg(ACTA1-Capn3*)37.9Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Tg(ACTA1-Capn3*)39.1Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Tg(ACTA1-Capn3*)41.1Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Tg(ACTA1-Capn3*)42Spc/0
involves: BALB/c * C57BL/6J 		abnormal gait J:77348
centrally nucleated skeletal muscle fibers J:77348
decreased skeletal muscle mass J:77348
kyphosis J:77348
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory