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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Plcb4
phospholipase C, beta 4
MGI:107464
32 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Plcb4tm1b(EUCOMM)Wtsi/Plcb4tm1b(EUCOMM)Wtsi
C57BL/6N-Plcb4tm1b(EUCOMM)Wtsi/Tcp 		abnormal auditory brainstem response J:211773
abnormal gait J:211773
abnormal gallbladder morphology J:211773
abnormal locomotor behavior J:211773
abnormal uterus morphology J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased total body fat amount J:211773
enlarged gallbladder J:211773
hydrometra J:211773
increased bone mineral content J:211773
increased grip strength J:211773
increased lean body mass J:211773
increased vertical activity J:211773
preweaning lethality, incomplete penetrance J:211773
Plcb4tm1Dwu/Plcb4tm1Dwu
involves: 129S1/Sv 		abnormal locomotor coordination J:51664
abnormal Purkinje cell innervation J:51664
abnormal rod electrophysiology J:77638
abnormal vision J:77638
ataxia J:51664
impaired coordination J:51664
short stride length J:51664
Plcb4tm1Hssh/Plcb4tm1Hssh
Not Specified 		abnormal cerebellar foliation J:43077
abnormal cerebellum external granule cell layer morphology J:43077
abnormal gait J:43077
abnormal synaptic transmission J:43077
ataxia J:43077
decreased body size J:43077
decreased locomotor activity J:43077
normal muscle phenotype J:43077
postnatal lethality, incomplete penetrance J:43077
normal skeleton phenotype J:43077
small cerebellum J:43077
Plcb4tm1Tyo/Plcb4tm1Tyo
involves: C57BL/6J 		abnormal nervous system physiology J:72939
reduced long-term depression J:72939
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory