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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gata6
GATA binding protein 6
MGI:107516
30 phenotypes from 10 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gata6tm1Eno/Gata6tm1Eno
either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) 		abnormal visceral endoderm morphology J:111824
embryonic lethality between implantation and somite formation, complete penetrance J:111824
Gata6tm1Gsv/Gata6tm1Gsv
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB) 		abnormal endoderm development J:52029
decreased inner cell mass proliferation J:52029
embryonic lethality between implantation and somite formation, complete penetrance J:52029
Gata6tm1Hadj/Gata6+
involves: 129S4/SvJae * C57BL/6 * CD-1 		prenatal lethality, incomplete penetrance J:226600
reduced fertility J:226600
Gata6tm1Kgac/Gata6tm1Kgac
involves: 129S1/Sv 		normal respiratory system phenotype J:134027
Gata6tm1Msp/Gata6tm1Msp
involves: 129X1/SvJ * C57BL/6 * CD-1 		abnormal endoderm development J:51304
decreased embryo size J:51304
embryonic growth retardation J:51304
embryonic lethality between implantation and somite formation, complete penetrance J:51304
increased embryonic epiblast cell apoptosis J:51304
increased embryonic tissue cell apoptosis J:51304
small embryonic epiblast J:51304
Gata6tm1Sad/Gata6tm1Sad
involves: 129S1/Sv * 129X1/SvJ 		abnormal liver bud morphology J:97579
normal cardiovascular system phenotype J:97579
decreased embryo size J:97579
embryonic lethality during organogenesis, complete penetrance J:97579
Gata6tm2.1Sad/Gata6tm2.1Sad
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL 		no abnormal phenotype detected J:111388
Gata6tm2.1Sad/Gata6tm2.1Sad
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		preaxial polydactyly J:205405
Gata6tm2.1Sad/Gata6tm2.1Sad
Tg(Vil1-cre)997Gum/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL 		embryonic lethality during organogenesis, complete penetrance J:111388
Gata6tm2.1Sad/Gata6tm2.2Sad
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N * SJL 		embryonic lethality during organogenesis, complete penetrance J:111388
Gata6tm2.2Sad/Gata6+
involves: 129S1/Sv * 129X1/SvJ 		absent primitive endoderm J:213580
Gata6tm2.2Sad/Gata6+
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		abnormal primitive endoderm morphology J:217512
Gata6tm2.2Sad/Gata6tm2.2Sad
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		absent primitive endoderm J:217512
Gata6tm2.2Sad/Gata6tm2.2Sad
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N 		embryonic lethality, complete penetrance J:111388
Gata6tm2Msp/Gata6tm2Msp
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal cardiovascular system morphology J:107814
aortic arch hypoplasia J:107814
double outlet right ventricle J:107814
interrupted aortic arch J:107814
perimembraneous ventricular septal defect J:107814
perinatal lethality, complete penetrance J:107814
persistent truncus arteriosus J:107814
retroesophageal right subclavian artery J:107814
Gata6tm2Msp/Gata6tm2Msp
Tg(Tagln-cre)1Jjl/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N 		absent fetal ductus arteriosus J:107814
aortic arch hypoplasia J:107814
cyanosis J:107814
double outlet right ventricle J:107814
interrupted aortic arch J:107814
perimembraneous ventricular septal defect J:107814
perinatal lethality, complete penetrance J:107814
persistent truncus arteriosus J:107814
retroesophageal right subclavian artery J:107814
Gata6tm2Sad/Gata6tm2Sad
involves: 129S1/Sv * 129X1/SvJ 		embryonic lethality, complete penetrance J:111388
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory