Ly6a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ly6a
lymphocyte antigen 6 family member A
MGI:107527

25 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ly6a^tm1Grau/Ly6a⁺ involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:82052
Ly6a^tm1Grau/Ly6a^tm1Grau involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:82052
Ly6a^tm1Pmf/Ly6a^tm1Pmf B6.129P2-Ly6a^tm1Pmf	abnormal common myeloid progenitor cell morphology	J:81387
	abnormal definitive hematopoiesis	J:81387
	abnormal immunoglobulin level	J:42594
	abnormal myeloid leukocyte morphology	J:81387
	abnormal T cell proliferation	J:42594
	decreased granulocyte number	J:81387
	decreased megakaryocyte cell number	J:81387
	decreased monocyte cell number	J:81387
	increased bleeding time	J:81387
	increased lymphocyte cell number	J:81387
	normal mortality/aging	J:42594
	thrombocytopenia	J:81387
Ly6a^tm1Pmf/Ly6a^tm1Pmf C.129P2-Ly6a^tm1Pmf	abnormal common myeloid progenitor cell morphology	J:83409
	abnormal fat cell morphology	J:83409
	abnormal osteoblast differentiation	J:83409
	abnormal osteoblast physiology	J:83409
	abnormal osteoclast differentiation	J:83409
	decreased bone mineral content	J:83409
	decreased bone ossification	J:83409
	decreased bone strength	J:83409
	decreased bone trabecula number	J:83409
	decreased osteoclast cell number	J:83409
	decreased osteoid volume	J:83409
	osteoporosis	J:83409
Ly6a^tm1Pmf/Ly6a^tm1Pmf involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:42594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24