Ly6a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ly6a
lymphocyte antigen 6 family member A
MGI:107527

25 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ly6a^tm1Grau/Ly6a⁺ involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:82052
Ly6a^tm1Grau/Ly6a^tm1Grau involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:82052
Ly6a^tm1Pmf/Ly6a^tm1Pmf B6.129P2-Ly6a^tm1Pmf	abnormal common myeloid progenitor cell morphology	J:81387
	abnormal definitive hematopoiesis	J:81387
	abnormal immunoglobulin level	J:42594
	abnormal myeloid leukocyte morphology	J:81387
	abnormal T cell proliferation	J:42594
	decreased granulocyte number	J:81387
	decreased megakaryocyte cell number	J:81387
	decreased monocyte cell number	J:81387
	increased bleeding time	J:81387
	increased lymphocyte cell number	J:81387
	normal mortality/aging	J:42594
	thrombocytopenia	J:81387
Ly6a^tm1Pmf/Ly6a^tm1Pmf C.129P2-Ly6a^tm1Pmf	abnormal common myeloid progenitor cell morphology	J:83409
	abnormal fat cell morphology	J:83409
	abnormal osteoblast differentiation	J:83409
	abnormal osteoblast physiology	J:83409
	abnormal osteoclast differentiation	J:83409
	decreased bone mineral content	J:83409
	decreased bone ossification	J:83409
	decreased bone strength	J:83409
	decreased bone trabecula number	J:83409
	decreased osteoclast cell number	J:83409
	decreased osteoid volume	J:83409
	osteoporosis	J:83409
Ly6a^tm1Pmf/Ly6a^tm1Pmf involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:42594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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