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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
MGI:107558
41 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sema3am808Ddg/Sema3am808Ddg
involves: C3H/He * C57BL/6 		abnormal axon fasciculation J:159834
abnormal ophthalmic nerve morphology J:159834
Sema3am808Ddg/Sema3atm1Mcf
involves: 129S4/SvJae * C3H/He * C57BL/6 		abnormal axon fasciculation J:159834
abnormal ophthalmic nerve morphology J:159834
Sema3atm1.1Tyag/Sema3atm1.1Tyag
involves: C57BL/6 * CBA 		abnormal dendritic cell physiology J:161856
abnormal dorsal root ganglion morphology J:43443
abnormal enteric nervous system morphology J:121340
abnormal olfactory bulb morphology J:97369
abnormal paravertebral ganglion morphology J:43443
abnormal spinal nerve morphology J:43443
abnormal T cell physiology J:161856
abnormal trigeminal nerve morphology J:43443
abnormal vagus nerve morphology J:43443
decreased body size J:43443
decreased body weight J:43443
small olfactory bulb J:97369
Sema3atm1Mcf/Sema3a+
involves: 129S4/SvJae 		abnormal neuron differentiation J:127639
Sema3atm1Mcf/Sema3atm1Mcf
involves: 129S4/SvJae 		abnormal atrial thrombosis J:35824
abnormal cerebral cortex morphology J:35824
abnormal cerebral cortex pyramidal cell morphology J:35824
abnormal neuron differentiation J:127639
abnormal posture J:35824
abnormal rib morphology J:35824
abnormal sensory neuron innervation pattern J:35824
abnormal sternum morphology J:35824
asymmetric sternocostal joints J:35824
cervical vertebral fusion J:35824
decreased body size J:35824
decreased brain size J:35824
decreased food intake J:35824
decreased survivor rate J:35824
dilated heart right atrium J:35824
heart right ventricle hypertrophy J:35824
lethality at weaning, incomplete penetrance J:35824
postnatal lethality, incomplete penetrance J:35824
premature death J:35824
prenatal lethality, incomplete penetrance J:35824
normal respiratory system phenotype J:35824
rib fusion J:35824
split xiphoid process J:35824
thin cerebral cortex J:35824
weakness J:35824
Sema3atm1Mcf/Sema3atm1Mcf
Tg(Hoxb7-EGFP)33Cos/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal branching involved in ureteric bud morphogenesis J:135328
neonatal lethality, incomplete penetrance J:135328
postnatal lethality, complete penetrance J:135328
prenatal lethality, incomplete penetrance J:135328
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory