Cav3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cav3
caveolin 3
MGI:107570

43 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cav3^{em1(IMPC)Kmpc}/Cav3^{em1(IMPC)Kmpc} C57BL/6NTac-Cav3^{em1(IMPC)Kmpc}/Kmpc	abnormal ovary morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	absent liver	J:211773
	increased prepulse inhibition	J:211773
Cav3^tm1Mls/Cav3^tm1Mls involves: 129/Sv * C57BL/6J * SJL	abnormal myocardial fiber morphology	J:79453
	abnormal sarcolemma morphology	J:69965
	abnormal skeletal muscle fiber morphology	J:69965
	absent caveolae	J:79453
	cardiac fibrosis	J:79453
	cardiac hypertrophy	J:79453
	cardiomyopathy	J:79453
	decreased heart ventricle muscle contractility	J:79453
	dilated heart left ventricle	J:79453
	dystrophic muscle	J:69965
	heart left ventricle hypertrophy	J:79453
	increased circulating creatine kinase level	J:69965
	increased heart left ventricle wall thickness	J:79453
	increased variability of skeletal muscle fiber size	J:69965
	normal muscle phenotype	J:117199
	myopathy	J:69965
	skeletal muscle fiber necrosis	J:69965
	thick interventricular septum	J:79453
Cav3^tm1Ncnp/Cav3^tm1Ncnp involves: 129S4/SvJae * C57BL/6J	muscle degeneration	J:66558
Cav3^tm1Ncnp/Cav3^tm1Ncnp involves: 129S4/SvJae * C57BL/10	abnormal atrium myocardial trabeculae morphology	J:150127
	abnormal heart atrium morphology	J:150127
	abnormal muscle development	J:150127
	abnormal muscle fiber morphology	J:150127
	centrally nucleated skeletal muscle fibers	J:150127
	myocardial fiber disarray	J:150127
	thick ventricular wall	J:150127
Tg(Ckmm-Cav3)1Ysu/0 involves: C57BL/Slc * DBA/Slc	abnormal heart echocardiography feature	J:87692
	abnormal muscle physiology	J:67174
	abnormal myocardial fiber morphology	J:87692
	abnormal nitric oxide homeostasis	J:67174
	centrally nucleated skeletal muscle fibers	J:67174
	decreased body size	J:67174, J:87692
	decreased heart left ventricle size	J:87692
	hindlimb paralysis	J:67174, J:87692
	increased heart left ventricle muscle contractility	J:87692
	increased heart weight	J:87692
	increased myocardial fiber size	J:87692
	increased variability of skeletal muscle fiber size	J:67174
	kyphosis	J:67174, J:87692
	myopathy	J:67174
	postnatal growth retardation	J:67174, J:87692
	skeletal muscle atrophy	J:67174
	skeletal muscle fiber degeneration	J:67174
	thick interventricular septum	J:87692
	thick ventricular wall	J:87692

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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