Sipa1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sipa1
signal-induced proliferation associated gene 1
MGI:107576

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sipa1^{tm1b(EUCOMM)Hmgu}/Sipa1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Sipa1^{tm1b(EUCOMM)Hmgu}/H	head bobbing	J:211773
Sipa1^tm1Nm/Sipa1⁺ involves: 129P2/OlaHsd * C57BL/6	decreased erythrocyte cell number	J:97239
	enlarged spleen	J:97239
	increased chronic myelocytic leukemia incidence	J:97239
	increased leukocyte cell number	J:97239
Sipa1^tm1Nm/Sipa1^tm1Nm involves: 129P2/OlaHsd * C57BL/6	abnormal bone marrow cell morphology/development	J:97239
	abnormal definitive hematopoiesis	J:97239
	anemia	J:97239
	enlarged spleen	J:97239
	extramedullary hematopoiesis	J:97239
	increased bone marrow cell number	J:97239
	increased chronic myelocytic leukemia incidence	J:97239
	increased granulocyte number	J:97239
	increased hematopoietic stem cell number	J:97239
	increased leukocyte cell number	J:97239
	pancytopenia	J:97239
	spleen hyperplasia	J:97239

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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