Srebf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Srebf2
sterol regulatory element binding factor 2
MGI:107585

15 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Srebf2^{Gt(YTA054)Byg}/Srebf2^{Gt(YTA054)Byg} involves: 129P2/OlaHsd * C57BL/6J	prenatal lethality, complete penetrance	J:176249
Srebf2^{Gt(YTA054)Byg}/Srebf2^lop13 involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J	abnormal lens fiber morphology	J:176249
	abnormal skin condition	J:176249
	cataract	J:176249
	prenatal lethality, incomplete penetrance	J:176249
Srebf2^lop13/Srebf2^lop13 STOCK Srebf2^lop13/J	abnormal lens fiber morphology	J:176249
	abnormal skin condition	J:176249
	cataract	J:13874, J:176249
	decreased brain cholesterol level	J:176249
	decreased cholesterol level	J:176249
	decreased liver cholesterol level	J:176249
	nuclear cataract	J:176249
	normal vision/eye phenotype	J:13874
Srebf2^tm1Jdh/Srebf2^tm1Jdh Speer6-ps1^{Tg(Alb-cre)21Mgn}/? involves: 129S6/SvEvTac * C57BL/6 * DBA	abnormal lipid homeostasis	J:241873
	decreased body weight	J:241873
	decreased circulating cholesterol level	J:241873
	decreased circulating triglyceride level	J:241873
	decreased liver cholesterol level	J:241873
	decreased liver triglyceride level	J:241873

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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