Scn9a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scn9a
sodium channel, voltage-gated, type IX, alpha
MGI:107636

26 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scn9a^em1Wlf/Scn9a⁺ C57BL/6J-Scn9a^em1Wlf	abnormal action potential	J:329231
	abnormal nervous system electrophysiology	J:329231
	normal behavior/neurological phenotype	J:329231
	increased single cell response intensity	J:329231
	normal nervous system phenotype	J:329231
Scn9a^em1Wlf/Scn9a^em1Wlf C57BL/6J-Scn9a^em1Wlf	abnormal action potential	J:329231
	abnormal nervous system electrophysiology	J:329231
	behavior/neurological phenotype	J:329231
	increased single cell response intensity	J:329231
	nervous system phenotype	J:329231
Scn9a^tm1.1Jwo/Scn9a^tm1.1Jwo involves: 129	neonatal lethality, complete penetrance	J:92442
Scn9a^tm1.1Naas/Scn9a^tm1.1Naas B6.129-Scn9a^tm1.1Naas	abnormal kindling response	J:154118
Scn9a^tm1.1Naas/Scn9a^tm1.1Naas involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal seizure response to electrical stimulation	J:154118
	minimal clonic seizures	J:154118
Scn9a^tm1.1Vlcg/Scn9a^tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671
Scn9a^tm1Dgen/Scn9a⁺ involves: 129P2/OlaHsd * C57BL/6	increased prepulse inhibition	J:101679
Scn9a^tm1Dgen/Scn9a^tm1Dgen B6.129P2-Scn9a^tm1Dgen/J	neonatal lethality, complete penetrance	J:223425
Scn9a^tm1Dgen/Scn9a^tm1Dgen C.129P2(B6)-Scn9a^tm1Dgen	neonatal lethality, complete penetrance	J:223425
Scn9a^tm1Dgen/Scn9a^tm1Dgen either: (involves: 129P2/OlaHsd * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)	abnormal action potential	J:223425
	abnormal mechanical nociception	J:223425
	abnormal nociception after inflammation	J:223425
	abnormal renal/urinary system morphology	J:223425
	abnormal synaptic transmission	J:223425
	anosmia	J:223425
	decreased body size	J:223425
	dermatitis	J:223425
	hypoalgesia	J:223425
	increased chemical nociceptive threshold	J:223425
	increased thermal nociceptive threshold	J:223425
	postnatal lethality, incomplete penetrance	J:223425
Scn9a^tm1Dgen/Scn9a^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	perinatal lethality, complete penetrance	J:101679
Scn10a^tm2(cre)Jwo/Scn10a⁺ Scn9a^tm1Jwo/Scn9a^tm1Jwo involves: 129	abnormal nociception after inflammation	J:92442
	abnormal pain threshold	J:92442
	increased thermal nociceptive threshold	J:92442

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