Ifngr1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ifngr1
interferon gamma receptor 1
MGI:107655

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Bres/Apoe^tm1Bres Ifngr1^tm1Agt/Ifngr1^tm1Agt involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	abnormal apolipoprotein level	J:40921
	decreased susceptibility to atherosclerosis	J:40921
	increased circulating cholesterol level	J:40921
	increased circulating phospholipid level	J:40921
Fas^lpr/Fas^lpr Ifnar1^tm1Agt/Ifnar1^tm1Agt Ifngr1^tm1Agt/Ifngr1^tm1Agt MRL.Cg-Ifngr1^tm1Agt Ifnar1^tm1Agt Fas^lpr	decreased anti-nuclear antigen antibody level	J:92084
	decreased autoantibody level	J:92084
	decreased IgG level	J:92084
	decreased susceptibility to systemic lupus erythematosus	J:92084
	glomerulonephritis	J:92084
	increased IgG level	J:92084
	increased susceptibility to systemic lupus erythematosus	J:92084
	increased urine protein level	J:92084
	salivary gland inflammation	J:92084
	small lymph nodes	J:92084
Fas^lpr/Fas^lpr Ifngr1^tm1Agt/Ifngr1^tm1Agt MRL.Cg-Ifngr1^tm1Agt Fas^lpr	decreased anti-nuclear antigen antibody level	J:92084
	decreased autoantibody level	J:92084
	decreased IgA level	J:92084
	decreased IgG2a level	J:92084
	decreased IgG2b level	J:92084
	decreased IgG3 level	J:92084
	decreased IgM level	J:92084
	decreased susceptibility to systemic lupus erythematosus	J:92084
	glomerulonephritis	J:92084
	increased IgG1 level	J:92084
	increased IgG level	J:92084
	increased urine protein level	J:92084
	small lymph nodes	J:92084
Ifnar1^tm1Agt/Ifnar1^tm1Agt Ifngr1^tm1Agt/Ifngr1^tm1Agt involves: 129S2/SvPas * 129S7/SvEvBrd	abnormal immunoglobulin level	J:101427
	normal immune system phenotype	J:286237
	increased susceptibility to Herpesvirales infection	J:81243
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:115139
	increased susceptibility to Poxviridae infection	J:101427
	increased susceptibility to Togaviridae infection	J:81243
Ifngr1^tm1Agt/Ifngr1^tm1Agt Tg(GZMB-Tax)#Lera/0 involves: 129S7/SvEvBrd * C57BL/6	abnormal osteoclast differentiation	J:147601
	abnormal osteoclast physiology	J:147601
	decreased bone mineral density	J:147601
	increased circulating calcium level	J:147601
	increased osteoclast cell number	J:147601
	increased skeletal tumor incidence	J:147601
	increased tumor incidence	J:147601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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