Kif3b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif3b
kinesin family member 3B
MGI:107688

32 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif3b^{tm1b(EUCOMM)Wtsi}/Kif3b⁺ C57BL/6N-Kif3b^{tm1b(EUCOMM)Wtsi}/Wtsi	increased bone mineral content	J:211773
	increased grip strength	J:211773
Kif3b^{tm1b(EUCOMM)Wtsi}/Kif3b^{tm1b(EUCOMM)Wtsi} C57BL/6N-Kif3b^{tm1b(EUCOMM)Wtsi}/Wtsi	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Kif3b^tm1Noh/Kif3b⁺ involves: 129S4/SvJae * C57BL/6J	abnormal brain weight	J:286227
	abnormal dendritic mushroom spine morphology	J:286227
	abnormal dendritic spine morphology	J:286227
	abnormal hippocampus neuron morphology	J:286227
	abnormal response to novel object	J:286227
	abnormal social investigation	J:286227
	decreased corpus callosum size	J:286227
	decreased prepulse inhibition	J:286227
	decreased thigmotaxis	J:286227
	enhanced long-term potentiation	J:286227
	impaired spatial learning	J:286227
	impaired synaptic plasticity	J:286227
	increased exploration in new environment	J:286227
	increased grooming behavior	J:286227
	increased stereotypic behavior	J:286227
	reduced long-term depression	J:286227
	reduced NMDA-mediated synaptic currents	J:286227
	thin hippocampus stratum radiatum	J:286227
Kif3b^tm1Noh/Kif3b^tm1Noh involves: 129S4/SvJae * C57BL/6J	abnormal direction of heart looping	J:51419
	abnormal left-right axis patterning	J:51419
	abnormal spinal cord morphology	J:51419
	absent embryonic cilia	J:51419
	decreased embryo size	J:51419
	distended pericardium	J:51419
	embryonic lethality during organogenesis, complete penetrance	J:51419
	exencephaly	J:51419
	incomplete embryo turning	J:51419
	open neural tube	J:51419

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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