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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kif3a
kinesin family member 3A
MGI:107689
104 phenotypes from 4 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kif3a2a/Kif3a2a
involves: C3HeB/FeJ * C57BL/6J 		abnormal left-right axis patterning J:98216
abnormal spinal cord morphology J:98216
embryonic lethality during organogenesis, complete penetrance J:98216
Kif3atm1Gsn/Kif3a+
involves: 129S1/Sv * 129X1/SvJ 		abnormal embryo turning J:54575
abnormal heart looping J:54575
decreased embryo size J:54575
pericardial edema J:54575
Kif3atm1Gsn/Kif3atm1Gsn
involves: 129S1/Sv * 129X1/SvJ 		abnormal direction of heart looping J:54575
abnormal embryo turning J:54575
abnormal heart looping J:54575
abnormal left-right axis patterning J:54575
abnormal limb development J:54575
abnormal neural tube closure J:54575
abnormal primitive node morphology J:54575
absent embryonic cilia J:54575
caudal body truncation J:54575
decreased embryo size J:54575
delayed heart looping J:54575
embryonic lethality during organogenesis, complete penetrance J:54575
pericardial edema J:54575
situs inversus J:54575
small pharyngeal arch J:54575
Kif3atm1Gsn/Kif3atm2Gsn
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J 		decreased body size J:117033
decreased length of long bones J:117033
decreased long bone epiphyseal plate size J:117033
disorganized long bone epiphyseal plate J:117033
polydactyly J:117033
short limbs J:117033
Kif3atm1Gsn/Kif3atm2Gsn
Tg(Cdh16-cre)91Igr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR 		absent kidney epithelial cell primary cilium J:83293
enlarged kidney J:83293
increased blood urea nitrogen level J:83293
increased kidney apoptosis J:83293
kidney cortex cyst J:83293
kidney cyst J:83293
kidney failure J:83293
kidney medulla cyst J:83293
lethargy J:83293
polycystic kidney J:83293
postnatal growth retardation J:83293
renal interstitial fibrosis J:83293
renal tubule atrophy J:83293
Kif3atm1Gsn/Kif3atm2Gsn
Tg(FOXJ1-cre/ERT2)1Blh/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA 		abnormal brain morphology J:174694
Kif3atm1Gsn/Kif3atm2Gsn
Tg(Msx2-cre)5Rem/?
involves: 129S1/Sv * 129X1/SvJ 		abnormal limb bud morphology J:117033
Kif3atm1Noh/Kif3atm1Noh
involves: 129S4/SvJae * C57BL/6J 		abnormal developmental patterning J:55332
abnormal direction of heart looping J:55332
abnormal heart looping J:55332
abnormal left-right axis patterning J:55332
abnormal mesoderm development J:55332
abnormal somite development J:55332
absent embryonic cilia J:55332
absent nodal flow J:55332
decreased embryo size J:55332
distended pericardium J:55332
embryonic lethality during organogenesis, complete penetrance J:55332
hydrocephaly J:55332
incomplete embryo turning J:55332
myocardium hypoplasia J:55332
neural tube degeneration J:55332
pericardial effusion J:55332
wavy neural tube J:55332
Kif3atm2Gsn/Kif3atm2Gsn
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J 		abnormal basisphenoid bone morphology J:158523
abnormal cranial neural crest cell morphology J:158523
abnormal craniofacial bone morphology J:158523
abnormal craniofacial development J:158523
abnormal cranium morphology J:158523
abnormal frontal bone morphology J:158523
abnormal maxilla morphology J:158523
abnormal nasal bone morphology J:158523
abnormal nasal septum morphology J:158523
abnormal palatine bone morphology J:158523
abnormal premaxilla morphology J:158523
absent corpus callosum J:158523
absent mandibular condyloid process J:158523
absent mandibular ramus J:158523
anterior cranium occultum J:158523
broad frontonasal prominence J:158523
cleft secondary palate J:158523
increased cranial neural crest cell proliferation J:158523
ocular hypertelorism J:158523
short mandible J:158523
Kif3atm2Gsn/Kif3atm2Gsn
Tg(Col2a1-cre)1Bhr/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal actin cytoskeleton morphology J:121342
abnormal chondrocyte morphology J:121342
abnormal long bone epiphyseal plate morphology J:121342
abnormal long bone epiphyseal plate proliferative zone J:121342
abnormal long bone epiphysis morphology J:121342
abnormal long bone hypertrophic chondrocyte zone J:121342
abnormal rib morphology J:121342
decreased length of long bones J:121342
disproportionate dwarf J:121342
spina bifida occulta J:121342
thoracic vertebral fusion J:121342
Kif3atm2Gsn/Kif3atm2Gsn
Tg(Col2a1-cre)10Amc/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal basicranium morphology J:140779
abnormal endochondral bone ossification J:140779
disorganized long bone epiphyseal plate J:140779
disproportionate dwarf J:140779
polycystic kidney J:140779
Kif3atm2Gsn/Kif3atm2Gsn
Tg(NEUROG3-cre)1Herr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal cauda epididymis morphology J:210780
abnormal epididymis morphology J:210780
abnormal manchette disassembly J:210780
abnormal manchette morphology J:210780
abnormal manchette perinuclear ring morphology J:210780
abnormal outer dense fiber morphology J:210780
abnormal sperm axoneme morphology J:210780
abnormal sperm fibrous sheath morphology J:210780
abnormal sperm flagellum morphology J:210780
abnormal sperm head morphology J:210780
abnormal sperm nucleus morphology J:210780
abnormal spermatid morphology J:210780
abnormal spermatogenesis J:210780
decreased epididymis weight J:210780
decreased testis weight J:210780
disorganized sperm mitochondrial sheath J:210780
ectopic manchette J:210780
elongated manchette J:210780
male infertility J:210780
oligozoospermia J:210780
Kif3atm2Gsn/Kif3atm2Gsn
Tg(Rbp3-cre)528Jxm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal photoreceptor inner segment morphology J:63427
retina photoreceptor degeneration J:63427
short photoreceptor inner segment J:63427
short photoreceptor outer segment J:63427
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory