Dync2h1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dync2h1
dynein cytoplasmic 2 heavy chain 1
MGI:107736

35 phenotypes from 10 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dync2h1^b2b414Clo/Dync2h1^b2b414Clo C57BL/6J-Dync2h1^b2b414Clo	abnormal autopod morphology	J:175213
	abnormal coronary vessel morphology	J:175213
	abnormal craniofacial morphology	J:175213
	abnormal eye morphology	J:175213
	abnormal inferior vena cava morphology	J:175213
	abnormal lung lobe morphology	J:175213
	abnormal mouth morphology	J:175213
	abnormal respiratory system morphology	J:175213
	absent kidney	J:175213
	aorta pulmonary collateral arteries	J:175213
	balanced complete atrioventricular canal	J:175213
	common atrium	J:175213
	complete atrioventricular septal defect	J:175213
	coronary fistula	J:175213
	duplex kidney	J:175213
	holoprosencephaly	J:175213
	micrognathia	J:175213
	ocular hypotelorism	J:175213
	polydactyly	J:175213
	syndactyly	J:175213
	tracheoesophageal fistula	J:175213
	unbalanced complete atrioventricular canal, left dominant	J:175213
Dync2h1^{em1(IMPC)Rbrc}/Dync2h1^{em1(IMPC)Rbrc} C57BL/6NJcl-Dync2h1^{em1(IMPC)Rbrc}/Rbrc	preweaning lethality, complete penetrance	J:211773
Dync2h1^{Gt(RRM278)Byg}/Dync2h1^{Gt(RRM278)Byg} involves: 129P2/OlaHsd	abnormal brain morphology	J:100466
	abnormal direction of heart looping	J:100466
	embryonic lethality during organogenesis, complete penetrance	J:100466
Dync2h1^{Gt(RRM278)Byg}/Dync2h1^lln involves: 129P2/OlaHsd * C57BL/6J	abnormal brain morphology	J:100466
	abnormal direction of heart looping	J:100466
	embryonic lethality during organogenesis, complete penetrance	J:100466
Dync2h1^lln/Dync2h1^lln involves: C3HeB/FeJ * C57BL/6J	abnormal left-right axis patterning	J:98216
	abnormal spinal cord morphology	J:98216
	embryonic lethality during organogenesis, complete penetrance	J:98216
Dync2h1^lln/Dync2h1^lln involves: C57BL/6J	abnormal direction of heart looping	J:100466
	normal embryo phenotype	J:100466
	embryonic lethality during organogenesis, complete penetrance	J:100466
	exencephaly	J:100466
	polydactyly	J:100466
Dync2h1^m152Asp/Dync2h1^m152Asp Tg(Rr291-lacZ)#Mekk/0 involves: C57BL/6J * FVB/N	abnormal cerebral cortex morphology	J:136795
Dync2h1^m407Asp/Dync2h1^m407Asp Tg(Rr291-lacZ)#Mekk/0 involves: C57BL/6J * FVB/N	abnormal forebrain development	J:136795
Dync2h1^mmi/Dync2h1^mmi Tg(Hlxb9-GFP)1Tmj/? involves: C57BL/6J * FVB/N	abnormal motor neuron morphology	J:151965
Dync2h1^pol/Dync2h1^pol involves: C3H/HeJ * C57BL/6J	abnormal direction of heart looping	J:309102
	abnormal motile primary cilium morphology	J:309102
	embryonic lethality during organogenesis, complete penetrance	J:309102
	exencephaly	J:309102
	polydactyly	J:309102
Dync2h1^{Tg(Tyr)2307AOve}/Dync2h1^{Tg(Tyr)2307AOve} FVB/N-Dync2h1^{Tg(Tyr)2307AOve}	embryonic lethality during organogenesis, complete penetrance	J:175597
Dync2h1^ttn/Dync2h1^ttn Not Specified	abnormal cilium morphology	J:138139

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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