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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stra6
stimulated by retinoic acid gene 6
MGI:107742
42 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Stra6Gt(OST353837)Lex/Stra6Gt(OST353837)Lex
involves: 129S5/SvEvBrd * C57BL/6J 		decreased body length J:94077
decreased body weight J:94077
decreased lean body mass J:94077
postnatal growth retardation J:94077
Stra6tm1.1Jvli/Stra6tm1.1Jvli
involves: C57BL/6 * FVB/N 		abnormal choroid vasculature morphology J:214659
abnormal electroretinogram waveform feature J:214659
abnormal optic choroid morphology J:214659
abnormal retina inner nuclear layer thickness J:214659
abnormal retina melanin granule morphology J:214659
abnormal retina morphology J:214659
abnormal retina outer nuclear layer morphology J:214659
abnormal retina photoreceptor morphology J:214659
abnormal retina pigment epithelium morphology J:214659
abnormal sclera morphology J:214659
abnormal vitamin A level J:214659
abnormal vitamin A metabolism J:214659
blindness J:214659
decreased retina cone cell number J:214659
normal nervous system phenotype J:214659
retina cone cell degeneration J:214659
short photoreceptor outer segment J:214659
short retina rod cell outer segment J:214659
Stra6tm1Jvli/Stra6tm1Jvli
involves: C57BL/6 		abnormal cranium morphology J:214659
decreased body size J:214659
decreased body weight J:214659
dilated brain ventricle J:214659
enlarged cranium J:214659
hydrocephaly J:214659
postnatal lethality, complete penetrance J:214659
Stra6tm1Jwu/Stra6tm1Jwu
B6.129-Stra6tm1Jwu 		abnormal vitamin A metabolism J:211118
normal homeostasis/metabolism phenotype J:211118
normal immune system phenotype J:211118
Stra6tm1Nbg/Stra6tm1Nbg
involves: 129 * C57BL/6J 		abnormal cone electrophysiology J:196841
abnormal retinol level J:196841
abnormal rod electrophysiology J:196841
decreased retina cone cell number J:196841
microphthalmia J:196841
persistent hyperplastic primary vitreous J:196841
short photoreceptor inner segment J:196841
short photoreceptor outer segment J:196841
Stra6tm1Nbg/Stra6tm1Nbg
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal adipocyte glucose uptake J:203449
abnormal protein level J:203449
abnormal retina pigment epithelium morphology J:203449
normal embryo phenotype J:203449
improved glucose tolerance J:203449
increased insulin sensitivity J:203449
normal mortality/aging J:203449
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory