About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gfer
growth factor, augmenter of liver regeneration
MGI:107757
38 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Gfertm1(KOMP)Mbp/Gfer+
involves: C57BL/6J * C57BL/6N 		abnormal hepatocyte mitochondrial morphology J:224792
abnormal hepatocyte physiology J:224792
abnormal lipid oxidation J:224792
abnormal mitochondrial crista morphology J:224792
abnormal mitochondrial physiology J:224792
decreased hepatocyte mitochondrial DNA content J:224792
decreased hepatocyte proliferation J:224792
decreased mitochondrial number J:224792
dilated mitochondrion J:224792
impaired liver regeneration J:224792
increased susceptibility to injury J:224792
oxidative stress J:224792
Gfertm1(KOMP)Mbp/Gfertm1(KOMP)Mbp
involves: C57BL/6J * C57BL/6N 		embryonic lethality, complete penetrance J:224792
Gfertm1.1Crg/Gfertm1.1Crg
involves: 129 * C57BL/6 		abnormal hepatocyte morphology J:227242
abnormal mitochondrial chromosome morphology J:227242
oxidative stress J:227242
Gfertm1.1Crg/Gfertm1.1Crg
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * C57BL/6 * DBA 		abnormal cellular respiration J:227242
abnormal endoplasmic reticulum morphology J:227242
abnormal hepatocyte mitochondrial morphology J:227242
abnormal liver morphology J:227242
abnormal liver physiology J:227242
abnormal mitochondrial crista morphology J:227242
abnormal mitochondrial shape J:227242
abnormal oval cell physiology J:227242
decreased body weight J:227242
decreased liver cholesterol level J:227242
decreased mitochondrial number J:227242
dilated mitochondrion J:227242
focal hepatic necrosis J:227242
hepatic necrosis J:227242
hepatic steatosis J:227242
increased circulating alanine transaminase level J:227242
increased hepatocellular carcinoma incidence J:227242
increased hepatocyte apoptosis J:227242
increased hepatocyte proliferation J:227242
increased liver cholesterol level J:227242
increased liver triglyceride level J:227242
increased liver weight J:227242
liver fibrosis J:227242
liver inflammation J:227242
macrovesicular hepatic steatosis J:227242
microvesicular hepatic steatosis J:227242
pale liver J:227242
Gfertm1.2Crg/Gfertm1.2Crg
involves: 129 * C57BL/6 * FVB/N 		embryonic lethality, complete penetrance J:227242
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory