Gadd45b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gadd45b
growth arrest and DNA-damage-inducible 45 beta
MGI:107776

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gadd45a^tm1Ajf/Gadd45a^tm1Ajf Gadd45b^tm1Daa/Gadd45b^tm1Daa Gadd45g^tm1Mhol/Gadd45g^tm1Mhol either: (involves: 129X1/SvJ) or (involves: 129P2/OlaHsd * 129X1/SvJ)	increased cell proliferation	J:110650
Gadd45b^tm1Flv/Gadd45b^tm1Flv Gadd45g^tm1Flv/Gadd45g^tm1Flv involves: 129S1/Sv * 129S6/SvEvTac	abnormal T-helper 1 cell differentiation	J:87396
Gadd45b^tm1Flv/Gadd45b^tm1Flv Gadd45g^tm1Flv/Gadd45g^tm1Flv involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6	glomerulonephritis	J:118837
	increased anti-double stranded DNA antibody level	J:118837
	increased anti-histone antibody level	J:118837
	increased IgG1 level	J:118837
	increased IgM level	J:118837
	increased mature B cell number	J:118837
	increased memory T cell number	J:118837
	renal glomerular immunoglobulin deposits	J:118837
	spleen hyperplasia	J:118837

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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