Mesp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mesp1
mesoderm posterior 1
MGI:107785

30 phenotypes from 4 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mesp1/Mesp2^tm1Ysa/Mesp1/Mesp2^tm1Ysa involves: C57BL/6 * CBA * ICR	abnormal blood vessel morphology	J:62984
	abnormal ectoderm development	J:62984
	abnormal endoderm development	J:62984
	abnormal gastrulation	J:62984
	abnormal mesoderm development	J:62984
	abnormal primitive streak formation	J:62984
	absent heart	J:62984
	absent mesoderm	J:62984
	absent paraxial mesoderm	J:62984
	absent somites	J:62984
	decreased embryo size	J:62984
	embryonic lethality during organogenesis, complete penetrance	J:62984
Mesp1^tm1Ysa/Mesp1^tm3Ysa involves: C57BL/6 * CBA * ICR	abnormal mesoderm development	J:55840
Mesp1^tm1Ysa/Mesp1^tm3Ysa involves: C57BL/6 * CBA * ICR	abnormal primitive streak morphology	J:55840
Mesp1^tm3Ysa/Mesp1^tm3Ysa involves: C57BL/6 * CBA	abnormal cardiogenic mesoderm morphology	J:55840
	abnormal heart development	J:49903, J:55840
	abnormal heart looping	J:49903, J:55840
	abnormal heart tube morphology	J:55840
	abnormal mesoderm development	J:55840
	abnormal neural fold formation	J:49903
	abnormal neural tube morphology	J:49903
	abnormal paraxial mesoderm morphology	J:55840
	abnormal primitive streak morphology	J:55840
	cardia bifida	J:49903, J:55840
	decreased embryo size	J:49903
	decreased somite size	J:49903
	delayed embryo turning	J:49903
	delayed neural tube closure	J:49903
	embryonic growth arrest	J:49903, J:55840
	embryonic growth retardation	J:49903, J:55840
	embryonic lethality during organogenesis, complete penetrance	J:49903, J:55840
	failure of initiation of embryo turning	J:49903
	microcephaly	J:49903
Mesp1^tm4Ysa/Mesp1^tm4Ysa involves: C57BL/6 * CBA * ICR	absent heart	J:71983
	absent somites	J:71983
	disorganized embryonic tissue	J:71983
	prenatal lethality, complete penetrance	J:71983

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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