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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mesp1
mesoderm posterior 1
MGI:107785
114 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Adgrg6em2Jlp/Adgrg6em3Jlp
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj 		no abnormal phenotype detected J:315981
Adgrg6em3Jlp/Adgrg6em3Jlp
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj 		no abnormal phenotype detected J:315981
Chd7Gt(XK403)Byg/Chd7+
Mesp1tm2(cre)Ysa/Mesp1+
either: (involves: 129P2/OlaHsd * C57BL/6 * CBA) or (involves: 129P2/OlaHsd * C57BL/6 * CBA * CD-1) 		abnormal fourth pharyngeal arch artery morphology J:154590
abnormal sixth pharyngeal arch artery morphology J:154590
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6J * C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj 		abnormal atrioventricular cushion morphology J:225736
abnormal cardiac outflow tract development J:225736
abnormal coronary vein morphology J:225736
abnormal fetal cardiomyocyte physiology J:225736
abnormal heart development J:225736
abnormal innervation J:225736
abnormal myocardial trabeculae morphology J:225736
abnormal myocardium compact layer morphology J:225736
abnormal truncus arteriosus septation J:225736
abnormal vein morphology J:225736
aortopulmonary window J:225736
atrioventricular septal defect J:225736
normal cardiovascular system phenotype J:225736
common atrioventricular valve J:225736
congestive heart failure J:225736
double inlet heart left ventricle J:225736
double outlet right ventricle J:225736
edema J:225736
hemorrhage J:225736
interrupted aortic arch, type b J:225736
lethality throughout fetal growth and development, incomplete penetrance J:225736
perinatal lethality, complete penetrance J:225736
thin ventricle myocardium compact layer J:225736
thin ventricular wall J:225736
Cited2tm1Bha/Cited2tm2Bha
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129 * C57BL/6 * CBA * SJL 		ventricular septal defect J:137951
Dph1tm1.1Cmch/Dph1tm1.1Cmch
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj 		normal craniofacial phenotype J:214744
postnatal lethality, incomplete penetrance J:214744
Dph1tm2Bhr/Dph1+
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj 		embryonic lethality, complete penetrance J:214744
Dph1tm2Bhr/Dph1tm2Bhr
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj 		normal mortality/aging J:214744
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6NCrlj * CBA/JNCrlj 		aberrant origin of the right subclavian artery J:170879
abnormal cardiac epithelial to mesenchymal transition J:170879
abnormal cardiac neural crest cell migration J:170879
abnormal cardiac outflow tract development J:170879
abnormal cardiovascular development J:170879
abnormal common carotid artery morphology J:170879
abnormal fourth pharyngeal arch artery morphology J:170879
abnormal pharyngeal arch artery morphology J:170879
abnormal sixth pharyngeal arch artery morphology J:170879
abnormal third pharyngeal arch artery morphology J:170879
decreased heart right ventricle size J:170879
double outlet right ventricle J:170879
right aortic arch J:170879
ventricular septal defect J:170879
Fgf8tm2Moon/Fgf8tm1Mrc
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6 * CBA 		abnormal cardiac outflow tract development J:109475
abnormal heart tube morphology J:109475
bicuspid aortic valve J:109475
bicuspid pulmonary valve J:109475
common atrium J:109475
common ventricle J:109475
decreased cell proliferation J:109475
decreased heart right ventricle size J:109475
edema J:109475
embryonic lethality during organogenesis, incomplete penetrance J:109475
increased apoptosis J:109475
pericardial effusion J:109475
transposition of great arteries J:109475
Fgf10tm1Ska/Fgf10+
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6NCrlj * CBA/JNCrlj 		aberrant origin of the right subclavian artery J:170879
abnormal aortic arch morphology J:170879
abnormal cardiac outflow tract development J:170879
abnormal cardiovascular development J:170879
abnormal common carotid artery morphology J:170879
abnormal fourth pharyngeal arch artery morphology J:170879
abnormal pharyngeal arch artery morphology J:170879
abnormal sixth pharyngeal arch artery morphology J:170879
abnormal third pharyngeal arch artery morphology J:170879
decreased heart right ventricle size J:170879
double outlet right ventricle J:170879
right aortic arch J:170879
second pharyngeal arch hypoplasia J:170879
third pharyngeal arch hypoplasia J:170879
ventricular septal defect J:170879
Fgf10tm1Ska/Fgf10tm1Ska
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6NCrlj * CBA/JNCrlj 		aberrant origin of the right subclavian artery J:170879
abnormal aortic arch morphology J:170879
abnormal cardiac epithelial to mesenchymal transition J:170879
abnormal cardiac neural crest cell migration J:170879
abnormal cardiac outflow tract development J:170879
abnormal cardiovascular development J:170879
abnormal common carotid artery morphology J:170879
abnormal fourth pharyngeal arch artery morphology J:170879
abnormal pharyngeal arch artery morphology J:170879
abnormal sixth pharyngeal arch artery morphology J:170879
abnormal third pharyngeal arch artery morphology J:170879
decreased heart right ventricle size J:170879
double outlet right ventricle J:170879
second pharyngeal arch hypoplasia J:170879
third pharyngeal arch hypoplasia J:170879
ventricular septal defect J:170879
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S/SvEv * C57BL/6NCrlj * CBA/JNCrlj 		embryonic lethality, complete penetrance J:214744
Hacd2tm1b(EUCOMM)Hmgu/Hacd2tm1c(EUCOMM)Hmgu
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj 		no abnormal phenotype detected J:333944
Hey1tm1Kkb/Hey1tm1Kkb
Mesp1tm2(cre)Ysa/Mesp1+
Tg(CAG-cat,-Notch1)1Ysa/0
involves: 129S7/SvEvBrd * C3H * C57BL/6 * CBA 		abnormal atrioventricular cushion morphology J:108444
abnormal interventricular septum morphology J:108444
abnormal myocardial trabeculae morphology J:108444
Hic2Gt(E225A08)1.1Wrst/Hic2Gt(E225A08)1.1Wrst
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj 		atrial septal defect J:225226
edema J:225226
normal embryo phenotype J:225226
hemorrhage J:225226
lethality during fetal growth through weaning, incomplete penetrance J:225226
overriding aortic valve J:225226
prenatal lethality, incomplete penetrance J:225226
thin myocardium J:225226
ventricular septal defect J:225226
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig
Mesp1tm2(cre)Ysa/Mesp1+
B6.Cg-Mesp1tm2(cre)Ysa Kmt2dtm1.1Kaig 		abnormal heart tube morphology J:229890
embryonic growth retardation J:229890
embryonic lethality during organogenesis, complete penetrance J:229890
pericardial edema J:229890
Megf8tm1.2Ddg/Megf8tm1.2Ddg
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj 		normal cardiovascular system phenotype J:206541
Mesp1/Mesp2tm1Ysa/Mesp1+
Mesp1/Mesp2tm1Ysa/Mesp2tm8Ysa
involves: C57BL/6 * CBA * ICR 		rib fusion J:119678
Mesp1/Mesp2tm1Ysa/Mesp1+
Mesp1/Mesp2tm1Ysa/Mesp2tm9Ysa
involves: C57BL/6 * CBA * ICR 		rib fusion J:119678
Mesp1/Mesp2tm1Ysa/Mesp1+
Mesp1/Mesp2tm1Ysa/Mesp2tm10Ysa
involves: C57BL/6 * CBA * ICR 		abnormal vertebrae morphology J:119678
decreased body length J:119678
fusion of vertebral arches J:119678
Mesp1/Mesp2tm1Ysa/Mesp1+
Mesp1/Mesp2tm1Ysa/Mesp2tm11Ysa
involves: C57BL/6 * CBA * ICR 		abnormal vertebrae morphology J:119678
vertebral fusion J:119678
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm3Bld
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal accessory nerve morphology J:112457
abnormal aortic arch morphology J:112457
abnormal cardiac neural crest cell migration J:112457
abnormal cardiac outflow tract development J:112457
abnormal cranial neural crest cell migration J:112457
abnormal fourth pharyngeal pouch morphology J:112457
abnormal interventricular septum morphology J:112457
abnormal mandibular nerve branching J:112457
abnormal mesenchyme morphology J:112457
abnormal pharyngeal arch artery morphology J:112457
abnormal pharyngeal arch morphology J:112457
abnormal vagus nerve morphology J:112457
absent fourth pharyngeal arch J:112457
absent fourth pharyngeal arch artery J:112457
absent sixth pharyngeal arch J:112457
absent sixth pharyngeal arch artery J:112457
absent third pharyngeal arch J:112457
absent third pharyngeal arch artery J:112457
athymia J:112457
normal craniofacial phenotype J:112457
ear lobe hypoplasia J:112457
glossopharyngeal nerve hypoplasia J:112457
persistent truncus arteriosus J:112457
pharynx hypoplasia J:112457
second pharyngeal arch hypoplasia J:112457
thymus hypoplasia J:112457
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm5Bld
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal neural crest cell migration J:112457
absent fourth pharyngeal arch J:112457
absent fourth pharyngeal arch artery J:112457
athymia J:112457
normal cardiovascular system phenotype J:112457
normal hearing/vestibular/ear phenotype J:112457
Mesp1tm2(cre)Ysa/Mesp1+
Rbpjtm1Hon/Rbpjtm1Hon
Tg(CAG-cat,-Notch1)1Ysa/0
involves: 129P2/OlaHsd * C3H * C57BL/6 * CBA 		abnormal heart development J:139209
abnormal heart morphology J:139209
Mesp1tm2(cre)Ysa/Mesp1+
Tg(CAG-cat,-Notch1)1Ysa/0
involves: C3H * C57BL/6 * CBA 		abnormal atrioventricular cushion morphology J:108444
abnormal heart development J:108444
abnormal heart shape J:108444
abnormal heart ventricle morphology J:108444
abnormal interventricular septum morphology J:108444
abnormal myocardial fiber morphology J:108444
abnormal myocardium layer morphology J:108444
abnormal sarcomere morphology J:108444
abnormal trabecula carnea morphology J:108444
decreased heart right ventricle size J:108444
dilated heart left ventricle J:108444
embryonic lethality during organogenesis, complete penetrance J:108444
enlarged heart J:139209
Mesp1tm2(cre)Ysa/Mesp1+
Pofut1tm1Ysa/Pofut1tm1Ysa
involves: C57BL/6 * CBA * SJL 		abnormal atrioventricular cushion morphology J:139209
abnormal cardiac epithelial to mesenchymal transition J:139209
abnormal heart development J:139209
embryonic lethality during organogenesis J:139209
myocardial trabeculae hypoplasia J:139209
Mesp1tm2(cre)Ysa/Mesp1+
Pofut1tm1Ysa/Pofut1tm1Ysa
Tg(CAG-cat,-Notch1)1Ysa/0
involves: C3H * C57BL/6 * CBA * SJL 		abnormal heart development J:139209
enlarged heart J:139209
Mesp1tm2(cre)Ysa/Mesp1+
Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
involves: C57BL/6NCrlj * CBA/JNCrlj 		abnormal cardiac epithelial to mesenchymal transition J:143444
abnormal cardiac outflow tract development J:143444
abnormal heart development J:143444
abnormal heart morphology J:143444
atrioventricular septal defect J:143444
bicuspid aortic valve J:143444
double outlet right ventricle J:143444
persistent truncus arteriosus J:143444
ventricular septal defect J:143444
Mesp1tm2(cre)Ysa/Mesp1+
Zic3tm2.1Jwb/Y
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * CBA/JNCrlj 		no abnormal phenotype detected J:192577
Mesp1tm3Ysa/Mesp1tm3Ysa
Mesp2tm3(cre)Ysa/Mesp2tm3(cre)Ysa
involves: C57BL/6 * CBA 		abnormal embryo development J:62984
abnormal embryonic growth/weight/body size J:62984
abnormal heart morphology J:62984
embryonic lethality during organogenesis, complete penetrance J:62984
Nodaltm1Mku/Nodaltm1Mku
Mesp1tm2(cre)Ysa/Mesp1+
Tg(Pitx2-lacZ)1Mbf/0
involves: 129S1/Sv * C57BL/6 * CBA 		abnormal heart looping J:167616
Pitx2tm1.1Mbf/Pitx2tm1.1Mbf
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6 * CBA 		abnormal heart left atrium auricular region morphology J:167616
heart right ventricle hypoplasia J:167616
Rbpjtm1Hon/Rbpjtm1Hon
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal atrioventricular cushion morphology J:139209
abnormal cardiac epithelial to mesenchymal transition J:139209
abnormal heart development J:139209
Setd5tm1c(EUCOMM)Wtsi/Setd5+
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj 		dilated heart ventricle J:314464
Setd5tm1c(EUCOMM)Wtsi/Setd5tm1c(EUCOMM)Wtsi
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj 		abnormal cardiac outflow tract development J:314464
abnormal heart atrium morphology J:314464
abnormal heart morphology J:314464
abnormal heart shape J:314464
abnormal interventricular groove morphology J:314464
common atrium J:314464
common ventricle J:314464
decreased embryo size J:314464
dilated heart J:314464
dilated heart atrium J:314464
dilated heart ventricle J:314464
embryonic lethality during organogenesis, complete penetrance J:314464
heart right ventricle hypoplasia J:314464
hemorrhage J:314464
pericardial effusion J:314464
Sp8tm1Smb/Sp8tm2Smb
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj 		abnormal face development J:200761
normal craniofacial phenotype J:200761
midline facial cleft J:200761
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory