Stra8 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stra8
stimulated by retinoic acid gene 8
MGI:107917

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Firrm^em1Gpt/Firrm^em1Gpt Stra8^{em1(GFP/cre)Smoc}/Stra8⁺ involves: C57BL/6JGpt	abnormal chromosomal synapsis	J:344887
	abnormal female meiosis	J:344887
	abnormal male meiosis	J:344887
	abnormal seminiferous tubule morphology	J:344887
	abnormal synaptonemal complex	J:344887
	absent oocytes	J:344887
	arrest of male meiosis	J:344887
	arrest of spermatogenesis	J:344887
	azoospermia	J:344887
	decreased male germ cell number	J:344887
	decreased oocyte number	J:344887
	decreased testis weight	J:344887
	female infertility	J:344887
	increased male germ cell apoptosis	J:344887
	infertility	J:344887
	male infertility	J:344887
	ovary degeneration	J:344887
	premature ovarian failure	J:344887
	small ovary	J:344887
	small seminiferous tubules	J:344887
	small testis	J:344887
Mettl3^em1Chhe/Mettl3^em1Chhe Mettl14^em1Chhe/Mettl14^em1Chhe Stra8^{em1(GFP/cre)Smoc}/Stra8⁺ involves: C57BL/6J	abnormal epigenetic regulation of gene expression	J:250428
	abnormal seminiferous tubule morphology	J:250428
	abnormal sperm head morphology	J:250428
	abnormal spermatid morphology	J:250428
	abnormal translation	J:250428
	arrest of spermiogenesis	J:250428
	asthenozoospermia	J:250428
	decreased sperm progressive motility	J:250428
	decreased testis weight	J:250428
	oligozoospermia	J:250428
	small testis	J:250428
	teratozoospermia	J:250428
Mettl3^em1Chhe/Mettl3^em1Chhe Stra8^{em1(GFP/cre)Smoc}/Stra8⁺ involves: C57BL/6J	abnormal epigenetic regulation of gene expression	J:250428
	normal reproductive system phenotype	J:250428
Mettl14^em1Chhe/Mettl14^em1Chhe Stra8^{em1(GFP/cre)Smoc}/Stra8⁺ involves: C57BL/6J	abnormal epigenetic regulation of gene expression	J:250428
	normal reproductive system phenotype	J:250428
Nanos2^tm1Ysa/Nanos2^tm1Ysa Stra8^tm1Ysa/Stra8⁺ involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)	abnormal male meiosis	J:205334
	abnormal male reproductive system physiology	J:205334
Nanos2^tm1Ysa/Nanos2^tm1Ysa Stra8^tm1Ysa/Stra8^tm1Ysa involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)	abnormal male meiosis	J:205334
	abnormal male reproductive system physiology	J:205334

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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