Rock1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rock1
Rho-associated coiled-coil containing protein kinase 1
MGI:107927

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lepr^db/Lepr^db Rock1^tm1Leiw/Rock1^tm1Leiw involves: 129S7/SvEvBrd * C57BLKS/J * FVB/N	abnormal mitochondrial physiology	J:182287
	albuminuria	J:182287
	enlarged kidney	J:182287
	expanded mesangial matrix	J:182287
	hyperglycemia	J:182287
	increased body size	J:182287
	increased body weight	J:182287
	increased kidney weight	J:182287
	increased renal glomerulus apoptosis	J:182287
	increased renal glomerulus basement membrane thickness	J:182287
	oxidative stress	J:182287
	normal renal/urinary system phenotype	J:182287

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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