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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sqstm1
sequestosome 1
MGI:107931
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg7tm1Tchi/Atg7tm1Tchi
Sqstm1tm1Keta/Sqstm1tm1Keta
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj 		abnormal hepatocyte morphology J:130839
decreased liver function J:130839
increased circulating alanine transaminase level J:130839
increased circulating alkaline phosphatase level J:130839
increased circulating aspartate transaminase level J:130839
Atg7tm1Tchi/Atg7tm1Tchi
Sqstm1tm1Keta/Sqstm1tm1Keta
Tg(Nes-cre)1Wme/0
involves: 129 * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj 		abnormal nervous system physiology J:130839
absent cerebral cortex pyramidal cells J:130839
absent hippocampus pyramidal cells J:130839
axon degeneration J:130839
decreased Purkinje cell number J:130839
increased neuron apoptosis J:130839
limb grasping J:130839
tremors J:130839
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory