Ndufs6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ndufs6
NADH:ubiquinone oxidoreductase core subunit S6
MGI:107932

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndufs6^em1(IMPC)Bay/Ndufs6^em1(IMPC)Bay C57BL/6N-Ndufs6^em1(IMPC)Bay/BayMmucd	prenatal lethality	J:211773
	preweaning lethality, complete penetrance	J:211773
Ndufs6^{Gt(AR0138)Wtsi}/Ndufs6^{Gt(AR0138)Wtsi} involves: 129P2/OlaHsd * C57BL/6	abnormal cardiac muscle relaxation	J:183619
	abnormal cardiovascular system physiology	J:183619
	abnormal mitochondrial morphology	J:183619
	abnormal respiratory electron transport chain	J:183619
	cardiac fibrosis	J:183619
	decreased heart ventricle muscle contractility	J:183619
	decreased left ventricle systolic pressure	J:183619
	decreased litter size	J:183619
	decreased mitochondrial size	J:183619
	enlarged heart	J:183619
	increased fatty acids level	J:183619
	increased heart left ventricle size	J:183619
	increased heart left ventricle weight	J:183619
	increased heart right ventricle size	J:183619
	increased heart right ventricle weight	J:183619
	increased heart ventricle size	J:183619
	increased heart weight	J:183619
	increased left ventricle diastolic pressure	J:183619
	premature death	J:183619
	weight loss	J:183619

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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