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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
MGI:107940
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Braftm1Mmcm/Braf+
Ezh2tm1.1Nesh/Ezh2+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB 		increased melanoma incidence J:239472
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Ezh2tm1.1Nesh/Ezh2+
Nrastm1.1Nesh/Nras+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB 		increased melanoma incidence J:239472
Ezh1tm1Jnw/Ezh1tm1Jnw
Ezh2tm1Tara/Ezh2tm1Tara
Tg(KRT14-cre)1Efu/0
involves: 129P2/OlaHsd 		abnormal hair follicle infundibulum morphology J:169295
abnormal hair follicle outer root sheath morphology J:169295
abnormal hair growth J:169295
absent gastric milk in neonates J:169295
epidermal hyperplasia J:169295
hair follicle degeneration J:169295
increased hair follicle apoptosis J:169295
normal integument phenotype J:169295
neonatal lethality, complete penetrance J:169295
small hair follicles J:169295
Ezh2tm1.1Nesh/Ezh2+
Nrastm1.1Nesh/Nras+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB 		normal neoplasm J:239472
Ezh2tm1Tara/Ezh2tm1Tara
Ightm2Cgn/?
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal immune system phenotype J:83216
Ezh2tm2Sho/Ezh2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Kdm6btm1.1Rbo/Kdm6btm1.1Rbo
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J * CBA/J 		cleft palate J:323190
normal craniofacial phenotype J:323190
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory