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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nkx3-2
NK3 homeobox 2
MGI:108015
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gli3tm1Alj/Gli3tm1Alj
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S6/SvEvTac * 129S7/SvEvBrd 		normal digestive/alimentary phenotype J:199664
normal mortality/aging J:199664
Gli3tm1Alj/Gli3tm1Alj
Nkx3-2tm1(cre)Wez/Nkx3-2+
Smotm2Amc/Smotm2Amc
involves: 129S6/SvEvTac * 129S7/SvEvBrd * 129X1/SvJ 		abnormal digestive system morphology J:199664
Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		normal digestive/alimentary phenotype J:199664
Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S7/SvEvBrd 		normal digestive/alimentary phenotype J:199664
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S7/SvEvBrd * 129X1/SvJ 		abnormal intestine development J:199664
Nkx3-2tm1(cre)Tsa/Nkx3-2+
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
involves: 129S7/SvEvBrd * C57BL/6 		abnormal digestive system development J:98520
abnormal enteric neuron morphology J:98520
abnormal forestomach-glandular stomach junction morphology J:98520
abnormal gastric parietal cell morphology J:98520
abnormal stomach epithelium morphology J:98520
abnormal stomach glandular epithelium morphology J:98520
abnormal stomach morphology J:98520
abnormal stomach pyloric region morphology J:98520
abnormal stomach smooth muscle circular layer morphology J:98520
small forestomach J:98520
small stomach J:98520
Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
Nkx3-1tm1Hha/Nkx3-1tm1Hha
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal axial skeleton morphology J:79198
abnormal cartilage development J:79198
abnormal cervical atlas morphology J:79198
abnormal lumbar vertebrae morphology J:79198
abnormal rib morphology J:79198
abnormal sclerotome morphology J:79198
abnormal vertebrae development J:79198
abnormal vertebral body morphology J:79198
kinked tail J:79198
lethality throughout fetal growth and development, complete penetrance J:79198
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		abnormal enteric neuron morphology J:199664
abnormal enterocyte proliferation J:199664
abnormal intestinal enteroendocrine cell morphology J:199664
abnormal intestinal goblet cell morphology J:199664
abnormal intestinal smooth muscle morphology J:199664
abnormal intestine development J:199664
abnormal intestine physiology J:199664
neonatal lethality, complete penetrance J:199664
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory