Ptprv Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptprv
protein tyrosine phosphatase receptor type V
MGI:108027

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atf4^tm1Tow/Atf4⁺ Ptprv^tm1Asmi/Ptprv⁺ either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J * NIH Black Swiss) or (involves: 129P2/OlaHsd * C57BL/6J * NIH Black Swiss)	decreased circulating glucose level	J:152695
	increased circulating insulin level	J:152695
	increased pancreatic beta cell proliferation	J:152695
Del(3Bglap2-Bglap)2Kry/+ Ptprv^tm1Kry/Ptprv^tm1Kry Tg(Col1a1-cre)1Kry/0 involves: 129S7/SvEvBrd * FVB	normal endocrine/exocrine gland phenotype	J:126780
	normal homeostasis/metabolism phenotype	J:126780
Lep^ob/Lep^ob Ptprv^tm1Asmi/Ptprv⁺ involves: 129P2/OlaHsd * C57BL/10J	increased circulating insulin level	J:145998
Lep^ob/Lep^ob Ptprv^tm1Asmi/Ptprv^tm1Asmi involves: 129P2/OlaHsd * C57BL/10J	decreased circulating glucose level	J:145998
	improved glucose tolerance	J:145998
	increased circulating insulin level	J:145998

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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