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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Scn10a
sodium channel, voltage-gated, type X, alpha
MGI:108029
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Braftm1Cpri/Braf+
Grprtm1Jfb/?
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * 129P2/OlaHsd * 129X1/SvJ 		normal behavior/neurological phenotype J:205122
Braftm1Cpri/Braf+
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * 129P2/OlaHsd 		abnormal dorsal root ganglion morphology J:205122
abnormal innervation J:205122
abnormal nervous system electrophysiology J:205122
abnormal neuron physiology J:205122
normal behavior/neurological phenotype J:205122
enhanced behavioral response to xenobiotic J:205122
excessive scratching J:205122
skin lesions J:205122
Braftm1Cpri/Braf+
Grptm1Jfb/Grptm1Jfb
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * 129P2/OlaHsd * 129X1/SvJ * C57BL/6J 		normal behavior/neurological phenotype J:205122
Hcn2tm1.1Lex/Hcn2tm1.1Lex
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * C57BL/6 		abnormal nociception after inflammation J:176663
abnormal touch/ nociception J:176663
increased chemical nociceptive threshold J:176663
increased thermal nociceptive threshold J:176663
Oprd1tm1.1Cgrf/Oprd1tm1.1Cgrf
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * C57BL/6J 		abnormal nociception after inflammation J:208176
normal behavior/neurological phenotype J:208176
decreased physiological sensitivity to xenobiotic J:208176
Oprm1tm1.1Cgrf/Oprm1tm1.1Cgrf
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * C57BL/6J 		abnormal behavioral response to addictive substance J:207536
normal behavior/neurological phenotype J:207536
normal homeostasis/metabolism phenotype J:207536
normal integument phenotype J:207536
S100a10tm1Jwo/S100a10tm1Jwo
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * C57BL/6 		abnormal pain threshold J:113256
allodynia J:113256
decreased single cell response intensity J:113256
Scn3atm1.1Jwo/Scn3atm1.1Jwo
Scn10atm2(cre)Jwo/Scn10a+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 		normal behavior/neurological phenotype J:199857
Scn10atm2(cre)Jwo/Scn10a+
Scn9atm1Jwo/Scn9atm1Jwo
involves: 129 		abnormal nociception after inflammation J:92442
abnormal pain threshold J:92442
increased thermal nociceptive threshold J:92442
Scn10atm2(cre)Jwo/Scn10a+
Slc17a6tm1Kldr/Slc17a6tm1Kldr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal behavior/neurological phenotype J:167752
Scn10atm2(cre)Jwo/Scn10a+
Il10ratm1.1Jack/Il10ratm1.1Jack
involves: 129P2/OlaHsd 		normal behavior/neurological phenotype J:326965
Scn10atm2(cre)Jwo/Scn10a+
Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp
involves: 129 * 129S6/SvEvTac * C57BL/6J 		normal behavior/neurological phenotype J:217087
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory