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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gcm1
glial cells missing homolog 1
MGI:108045
18 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gcm1tm1Hoso/Gcm1tm1Hoso
either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * CD-1) 		abnormal neuron differentiation J:175891
embryonic lethality during organogenesis, complete penetrance J:175891
Gcm1tm1Jcc/Gcm1+
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal placenta fetal blood space morphology J:186528
abnormal placenta labyrinth morphology J:186528
abnormal placental labyrinth vasculature morphology J:186528
abnormal syncytiotrophoblast morphology J:186528
embryo tissue necrosis J:186528
increased cell proliferation J:186528
increased mean systemic arterial blood pressure J:186528
increased placenta intervillous maternal lacunae size J:186528
thick placenta labyrinth J:186528
Gcm1tm1Jcc/Gcm1tm1Jcc
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal chorionic plate morphology J:63123
absent placental labyrinth J:63123
decreased embryo size J:63123
embryonic lethality, complete penetrance J:63123
Gcm1tm1Ral/Gcm1tm1Ral
involves: 129S1/Sv * 129X1/SvJ 		no abnormal phenotype detected J:77274
Gcm1tm1Weg/Gcm1tm1Weg
involves: 129S1/Sv * 129X1/SvJ 		abnormal extraembryonic tissue morphology J:61094
prenatal lethality J:61094
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory