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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bcl2l2
BCL2-like 2
MGI:108052
22 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bcl2l2Gt(ROSA)41Sor/Bcl2l2Gt(ROSA)41Sor
involves: 129S5/SvEvBrd 		abnormal CNS synapse formation J:137190
abnormal motor learning J:137190
abnormal Purkinje cell dendrite morphology J:137190
abnormal Purkinje cell mitochondrial morphology J:137190
abnormal seminiferous tubule morphology J:46386
decreased male germ cell number J:46386
decreased seminal vesicle weight J:46386
increased circulating follicle stimulating hormone level J:46386
male infertility J:46386
small testis J:46386
Bcl2l2Gt(ROSA)41Sor/Bcl2l2Gt(ROSA)41Sor
involves: 129S5/SvEvBrd * C57BL/6J 		abnormal Sertoli cell barrier morphology J:70212
absent Leydig cells J:70212
decreased germ cell number J:70212
decreased seminal vesicle weight J:70212
decreased Sertoli cell number J:70212
decreased testis weight J:70212
increased Leydig cell number J:70212
small seminiferous tubules J:70212
Bcl2l2tm1Sco/Bcl2l2tm1Sco
involves: 129S1/Sv * C57BL/6 * FVB/N 		abnormal reproductive system morphology J:50338
abnormal seminiferous tubule epithelium morphology J:50338
azoospermia J:50338
decreased Sertoli cell number J:50338
increased male germ cell apoptosis J:50338
male infertility J:50338
multinucleated giant male germ cells J:50338
small seminiferous tubules J:50338
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory