Rit1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rit1
Ras-like without CAAX 1
MGI:108053

29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rit1^em1(IMPC)Mbp/Rit1^em1(IMPC)Mbp C57BL/6N-Rit1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	anophthalmia	J:211773
	enlarged kidney	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased mean platelet volume	J:211773
	increased red blood cell distribution width	J:211773
Rit1^tm1.1Tumg/Rit1⁺ B6.Cg-Rit1^tm1.1Tumg	abnormal cardiovascular system physiology	J:277548
	abnormal heart echocardiography feature	J:277548
	abnormal heart morphology	J:277548
	anemia	J:277548
	cardiac fibrosis	J:277548
	decreased body height	J:277548
	decreased body length	J:277548
	decreased body weight	J:277548
	enlarged spleen	J:277548
	hemorrhage	J:277548
	hydrops fetalis	J:277548
	increased circulating aspartate transaminase level	J:277548
	increased heart weight	J:277548
	lethality during fetal growth through weaning, incomplete penetrance	J:277548
	postnatal lethality, incomplete penetrance	J:277548
	premature death	J:277548
	rectal prolapse	J:277548
	reduced female fertility	J:277548
	round head	J:277548
	short snout	J:277548
	thick ventricular wall	J:277548
Rit1^tm1.1Tumg/Rit1^tm1.1Tumg B6.Cg-Rit1^tm1.1Tumg	prenatal lethality	J:277548
Rit1^tm1Dand/Rit1^tm1Dand involves: 129S6/SvEvTac * Black Swiss	increased cellular sensitivity to hydrogen peroxide	J:183038

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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