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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Traf6
TNF receptor-associated factor 6
MGI:108072
6 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd28tm1Mak/Cd28tm1Mak
Tg(Cd4-cre)1Cwi/?
Traf6tm2Ywc/Traf6tm2Ywc
involves: 129S2/SvPas * C57BL/6 * DBA/2 		decreased interleukin-2 secretion J:130882
decreased T cell proliferation J:130882
increased activated T cell number J:130882
increased memory T cell number J:130882
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?
Traf6tm2Ywc/Traf6tm2Ywc
involves: C57BL/6 * DBA/2 		abnormal lymphocyte anergy J:130882
increased interleukin-2 secretion J:130882
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory