Sfrp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp2
secreted frizzled-related protein 2
MGI:108078

23 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sfrp2^C50F/Sfrp2^C50F involves: BALB/c * C3H/HeH	normal reproductive system phenotype	J:119228
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle B6;129-Sfrp2^tm1.1Brle/J	normal reproductive system phenotype	J:275639
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle involves: 129S7/SvEvBrd	syndactyly	J:186306
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle involves: 129S7/SvEvBrd * C57BL/6	abnormal chondrocyte physiology	J:186306
	abnormal long bone diaphysis morphology	J:186306
	brachydactyly	J:186306
	brachypodia	J:186306
	decreased length of long bones	J:186306
	delayed endochondral bone ossification	J:186306
	short metacarpal bones	J:186306
	short metatarsal bones	J:186306
	short radius	J:186306
	short ulna	J:186306
	syndactyly	J:186306
Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6	syndactyly	J:106551
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ * C57BL/6	normal limbs/digits/tail phenotype	J:138805
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ * CBA/N	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ * C57BL/6	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	polysyndactyly	J:138805
	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ * CBA/N	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	syndactyly	J:138805
Sfrp2^tm1Nat/Sfrp2^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:137889
Sfrp2^tm1Sato/Sfrp2^tm1Sato Not Specified	abnormal neuron differentiation	J:112802
	abnormal response of heart to induced stress	J:146963
	increased cardiac muscle contractility	J:146963

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24