Sfrp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp2
secreted frizzled-related protein 2
MGI:108078

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ involves: 129 * C57BL/6 * CBA	incomplete somite formation	J:135313
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6 * CBA	abnormal presomitic mesoderm morphology	J:135313
	incomplete embryo turning	J:135313
	incomplete somite formation	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6	abnormal craniofacial morphology	J:106551
	abnormal rostral-caudal axis patterning	J:106551, J:135313
	abnormal rostral-caudal body axis extension	J:106551
	abnormal somite development	J:106551
	decreased somite size	J:106551
	decreased thoracic vertebrae number	J:106551
	edema	J:106551
	incomplete somite formation	J:106551, J:135313
	lethality throughout fetal growth and development, complete penetrance	J:106551
	short limbs	J:106551
	syndactyly	J:106551
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	abnormal somite development	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	abnormal rostral-caudal body axis extension	J:135313
	abnormal somite development	J:135313
	craniorachischisis	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	decreased somite size	J:135313
	embryonic growth retardation	J:135313
	embryonic lethality, complete penetrance	J:135313
	fused somites	J:135313
	incomplete somite formation	J:135313
	open neural tube	J:135313
Sfrp2^C50F/Sfrp2^C50F Sfrp5^Q27stop/Sfrp5^Q27stop involves: BALB/c * C3H/HeH	abnormal seminiferous tubule morphology	J:119228
	kinked tail	J:119228
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle Sfrp4^tm1.1Boer/Sfrp4^tm1.1Boer involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * BALB/cJ	increased litter size	J:275639
	increased ovulation rate	J:275639

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24