Bin1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bin1
bridging integrator 1
MGI:108092

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bin1^tm1Gcp/Bin1^tm1Gcp involves: 129S6/SvEvTac * C57BL/6J	abnormal A band morphology	J:83753
	abnormal myocardial fiber morphology	J:83753
	abnormal sarcomere morphology	J:83753
	abnormal suckling behavior	J:83753
	normal cellular phenotype	J:83753
	diffuse Z line	J:83753
	disorganized myocardium	J:83753
	normal immune system phenotype	J:83753
	neonatal lethality, complete penetrance	J:83753
	thick ventricular wall	J:83753
	ventricular cardiomyopathy	J:83753
Bin1^tm1Gcp/Bin1^tm2Gcp Tg(Wap-cre)11738Mam/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	abnormal involution of the mammary gland	J:117330
	abnormal mammary gland embryonic development	J:117330
	endometrium inflammation	J:117330
	increased granulosa cell tumor incidence	J:117330
	increased incidence of tumors by chemical induction	J:117330
	increased mammary gland tumor incidence	J:117330
Bin1^tm2Gcp/Bin1⁺ Tg(Wap-cre)11738Mam/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	increased incidence of tumors by chemical induction	J:117330
	increased mammary gland tumor incidence	J:117330

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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