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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dvl3
dishevelled segment polarity protein 3
MGI:108100
30 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dvl1tm1Awb/Dvl1tm1Awb
Dvl3tm1Awb/Dvl3tm1Awb
involves: 129S6/SvEvTac * Black Swiss 		lethality throughout fetal growth and development, complete penetrance J:142392
normal nervous system phenotype J:142392
Dvl2tm1Awb/Dvl2+
Dvl3tm1Awb/Dvl3+
involves: 129S6/SvEvTac * Black Swiss 		abnormal cardiac outflow tract development J:142392
abnormal orientation of cochlear hair cell stereociliary bundles J:142392
double outlet right ventricle J:142392
persistent truncus arteriosus J:142392
transposition of great arteries J:142392
Dvl2tm1Awb/Dvl2+
Dvl3tm1Awb/Dvl3tm1Awb
involves: 129S6/SvEvTac * Black Swiss 		abnormal head morphology J:142392
abnormal heart shape J:142392
abnormal orientation of cochlear hair cell stereociliary bundles J:142392
absent tail J:142392
craniorachischisis J:142392
herniated abdominal wall J:142392
kinked tail J:142392
persistent truncus arteriosus J:142392
short rostral-caudal axis J:142392
short snout J:142392
short tail J:142392
small heart J:142392
Dvl2tm1Awb/Dvl2tm1Awb
Dvl3tm1Awb/Dvl3+
involves: 129S6/SvEvTac * Black Swiss 		abnormal heart looping J:142392
caudal body truncation J:142392
craniorachischisis J:142392
embryonic lethality, complete penetrance J:142392
pericardial effusion J:142392
Dvl2tm1Awb/Dvl2tm1Awb
Dvl3tm1Awb/Dvl3tm1Awb
involves: 129S6/SvEvTac * Black Swiss 		embryonic lethality, complete penetrance J:142392
Dvl3tm1Awb/Dvl3+
Vangl2Lp/Vangl2+
involves: 129S6/SvEvTac * A * Black Swiss 		abnormal neural tube morphology J:142392
abnormal orientation of cochlear hair cell stereociliary bundles J:142392
normal cardiovascular system phenotype J:142392
craniorachischisis J:142392
decreased cochlear outer hair cell number J:142392
exencephaly J:142392
incomplete rostral neuropore closure J:142392
increased cochlear hair cell number J:142392
inner ear hypoplasia J:142392
Dvl3tm1Awb/Dvl3+
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
ventricular septal defect J:189062
Dvl3tm1Awb/Dvl3+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
ventricular septal defect J:189062
Dvl3tm1Awb/Dvl3tm1Awb
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
ventricular septal defect J:189062
Dvl3tm1Awb/Dvl3tm1Awb
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S/Sv * Black Swiss * C57BL/6J * CBA/J 		normal nervous system phenotype J:142392
Dvl3tm1Awb/Dvl3tm1Awb
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm1(cre)Sev/Isl1+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * Black Swiss 		normal cardiovascular system phenotype J:142392
Dvl3tm1Awb/Dvl3tm1Awb
Vangl2Lp/Vangl2+
involves: 129S6/SvEvTac * A * Black Swiss 		abnormal cardiac outflow tract development J:142392
abnormal neural tube morphology J:142392
abnormal orientation of cochlear hair cell stereociliary bundles J:142392
craniorachischisis J:142392
decreased cochlear outer hair cell number J:142392
increased cochlear hair cell number J:142392
inner ear hypoplasia J:142392
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory