Slc12a3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc12a3
solute carrier family 12, member 3
MGI:108114

15 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc12a3^em3Gpt/Slc12a3^em3Gpt involves: C57BL/6	decreased circulating magnesium level	J:336073
	normal growth/size/body region phenotype	J:336073
	hypokalemia	J:336073
	increased urine potassium level	J:336073
Slc12a3^em3Gpt/Slc12a3^em4Gpt involves: C57BL/6	normal cardiovascular system phenotype	J:336073
	decreased circulating magnesium level	J:336073
	decreased physiological sensitivity to xenobiotic	J:336073
	normal growth/size/body region phenotype	J:336073
	hypokalemia	J:336073
	increased urine magnesium level	J:336073
	increased urine potassium level	J:336073
	polyuria	J:336073
Slc12a3^em4Gpt/Slc12a3^em4Gpt involves: C57BL/6	decreased circulating magnesium level	J:336073
	normal growth/size/body region phenotype	J:336073
	hypokalemia	J:336073
	increased urine potassium level	J:336073
	polyuria	J:336073
Slc12a3^tm1Ges/Slc12a3^tm1Ges involves: C57BL/6	abnormal physiological response to xenobiotic	J:161474
	abnormal renal sodium ion transport	J:161474
	decreased urine chloride ion level	J:161474
	decreased urine sodium level	J:161474
Slc12a3^tm1Ges/Slc12a3^tm1Ges Not Specified	abnormal distal convoluted tubule morphology	J:50596
	decreased circulating magnesium level	J:50596
	decreased systemic arterial blood pressure	J:50596
	decreased urine calcium level	J:50596

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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