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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prkg1
protein kinase, cGMP-dependent, type I
MGI:108174
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Prkg1tm1.1Arte/Prkg1tm1.1Arte
C57BL/6-Prkg1tm1.1Arte 		decreased cardiac output J:181180
decreased vasodilation J:181180
increased mean systemic arterial blood pressure J:181180
increased systemic arterial blood pressure J:181180
increased systemic arterial diastolic blood pressure J:181180
increased systemic arterial systolic blood pressure J:181180
Prkg1tm2.1Naw/Prkg1tm2.1Naw
Taglntm1(PRKG1*)Hfm/Tagln+
involves: 129S1/Sv * 129X1/SvJ 		decreased litter size J:134928
premature death J:134928
reduced female fertility J:134928
Prkg1tm2.1Naw/Prkg1tm2.1Naw
Taglntm2(PRKG1*)Hfm/Tagln+
involves: 129S1/Sv * 129X1/SvJ 		decreased litter size J:134928
premature death J:134928
reduced female fertility J:134928
Prkg1Tn(sb-rtTA)2497B.SB2Ove/Prkg1Tn(sb-rtTA)2497B.SB2Ove
involves: FVB/N 		postnatal lethality, complete penetrance J:175597
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory