Prx Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prx
periaxin
MGI:108176

22 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prx^{em1(IMPC)Rbrc}/Prx^{em1(IMPC)Rbrc} C57BL/6NJcl-Prx^{em1(IMPC)Rbrc}/Rbrc	decreased locomotor activity	J:211773
Prx^tm1Brp/Prx^tm1Brp involves: 129P2/Ola * C57BL/6	abnormal action potential	J:62566
	abnormal gait	J:62566
	abnormal myelination	J:62566
	abnormal nerve conduction	J:62566
	abnormal nervous system electrophysiology	J:62566
	abnormal respiratory mechanics	J:62566
	abnormal Schwann cell morphology	J:92662
	abnormal touch/ nociception	J:62566
	aphagia	J:62566
	decreased thermal nociceptive threshold	J:62566
	hyporesponsive to tactile stimuli	J:62566
	limb grasping	J:62566
	weight loss	J:62566
Prx^tm1Brp/Prx^tm1Brp involves: 129P2/OlaHsd	abnormal internode morphology	J:199744
	abnormal myelination	J:199744
	decreased nerve conduction velocity	J:199744
Prx^tm1Brp/Prx^tm1Brp Tg(Mpz/GJB1-Prx)#Brp/0 involves: 129P2/OlaHsd C57BL/6	abnormal Schwann cell morphology	J:185953
	normal nervous system phenotype	J:185953
Prx^tm2.1Brp/Prx^tm2.1Brp B6.129P2-Prx^tm2.1Brp	abnormal internode morphology	J:199744
	abnormal myelination	J:199744
	abnormal nerve conduction	J:199744
	abnormal Schwann cell morphology	J:199744
	absent Cajal-Retzius cell	J:199744
	normal behavior/neurological phenotype	J:199744
	decreased nerve conduction velocity	J:199744
	impaired coordination	J:199744
	increased Schwann cell number	J:199744
	normal integument phenotype	J:199744

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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